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Postdoctoral Researcher

2 months ago

Gainesville, Florida, United States University of Florida Full time
Job Opportunity

Job Title: Postdoctoral Scholar

Job Summary:

The University of Florida is seeking a highly skilled and motivated Postdoctoral Scholar to join our research team in the Burris laboratory. Our laboratory focuses on the chemical biology of nuclear receptors and drug development for various diseases, including neurodegenerative disorders, atherosclerosis, metabolic disorders, and cancer.

Key Responsibilities:

  • Characterize novel synthetic or natural chemical probes modulating the function of nuclear receptors in disease models.
  • Optimize such compounds for future clinical use.
  • Conduct research projects, including:
    • Characterization of LXR inverse agonists in models of cardiometabolic diseases.
    • Development of novel REV-ERB agonists targeting aging-related metabolic dysfunction, neuroinflammation, and neurodegeneration.
    • Characterization of TLX ligands in models of dementia.
    • Exploration of the pharmacology of ERR agonists in a range of disease models.
    • Identification of chemical tools for orphan nuclear receptors.

Requirements:

  • Ph.D. in organic chemistry within the last 3 years.
  • Experience in natural product chemistry.
  • Expertise in analytical tools HPLC and LC/MS.
  • Expertise in structure elucidation using different 2D NMR techniques.
  • Excellent oral communication and written skills in English, with good organizational and analytical abilities.
  • International publications as a first author.

Benefits:

  • Commensurate salary with education and experience.
  • Health insurance, retirement options, and paid leave.