Process Chemistry Director
2 weeks ago
Frontier Medicines is seeking a highly motivated individual to lead our Process Chemistry team in South San Francisco. As a Director/Senior Director, you will be responsible for developing scalable manufacturing processes for our small molecule pipeline.
Key Responsibilities- Lead internal and external resources to develop manufacturing processes
- Oversee CDMOs from process chemistry development through to drug substance manufacturing
- Develop manufacturing processes that are scalable, safe, cost-effective, and environmentally friendly
- Manage CRO/CDMOs, including selection, technology transfer, and cGMP API manufacturing
- Partner with Medicinal Chemistry on scale-up synthesis to facilitate candidate nomination
- Apply discipline excellence to solve synthesis, process design, production equipment, and scale-up challenges
- Collaborate with Quality Assurance and Regulatory to review analytical documents and approve as required
- Ph.D. in organic chemistry with at least 10+ years of experience in small molecule drug development and manufacturing in biotech and/or pharma industry
- Masters degree with 15+ years of relevant experience in a biotech or pharma setting
- Extensive experience with process chemistry development, scale-up, tech transfer, drug substance characterization, and working with CDMOs
- Experience in cGMP manufacturing, leveraging, and managing CRO/CDMOs for the manufacture of regulatory starting materials and drug substances
- Experience overseeing related areas for regulatory submissions and knowledge of current regulations
- Experience with quality by design (QbD), process validations, and statistical design of experiments (DOE) is preferred
- Experience with early through late-stage process development is strongly preferred
- Competitive salary range: $205,000 - $275,000
- Comprehensive benefits package, including health care, retirement plan, life insurance, and paid time off
- Opportunities for professional growth and development
- Collaborative and dynamic work environment
-
Director of Process Chemistry
2 weeks ago
South San Francisco, California, United States Frontier Medicines Full timeJob Title: Director/Sr. Director, Head of Process ChemistryFrontier Medicines is seeking a highly motivated individual to lead our Process Chemistry team in our South San Francisco office. As a key member of our Chemistry organization, you will be responsible for developing scalable manufacturing processes for our small molecule pipeline.Key...
-
Process Chemistry Director
4 weeks ago
South San Francisco, California, United States Frontier Medicines Full timeJob Title: Director/Sr. Director, Head of Process ChemistryFrontier Medicines is seeking a highly motivated individual to lead our Process Chemistry team in our South San Francisco office. As a key member of our development team, you will be responsible for developing scalable manufacturing processes for our small molecule pipeline.Key Responsibilities:Lead...
-
Director of Process Chemistry
4 weeks ago
San Leandro, California, United States Aralez Bio Full timeJob Title: Director of Process ChemistryAralez Bio is seeking a highly skilled and experienced Director of Process Chemistry to lead our process development and manufacturing capabilities. As a key member of our team, you will be responsible for developing, building, and guiding our process development and manufacturing operations to ensure the efficient...
-
Director of Process Chemistry
5 days ago
San Leandro, California, United States Aralez Bio Full timeAralez Bio is seeking a strategic and hands-on Director to develop, build, and guide our process development and manufacturing capabilities.The Director of Process Chemistry (Biocatalysis) will oversee and manage process development, tech transfer, and manufacturing operations, ensuring adherence to ISO-9001 and other regulatory standards.This role will...
-
Director of Process Chemistry
4 days ago
San Leandro, California, United States Aralez Bio Full timeAbout Aralez BioAralez Bio is a cutting-edge biotechnology company that specializes in the development and manufacturing of noncanonical amino acids. Our innovative products are designed to create innovative products that are good for people and the planet. With a proprietary enzyme platform, we unlock ncAAs by making their synthesis faster, cheaper, and...
-
Director of Peptide Chemistry Research
1 week ago
San Francisco, California, United States Johnson Service Group Full timeJohnson Service Group is seeking a highly skilled Director, Peptide Chemistry R&D to lead our Peptide Research Department in San Francisco.The ideal candidate will have a strong background in peptide chemistry and a proven track record of leading research teams. They will be responsible for overseeing peptide design, synthesis, and research projects, as well...
-
Director of Medicinal Chemistry
1 week ago
South San Francisco, California, United States Merck Sharp & Dohme Full timeJob DescriptionAre you a seasoned medicinal chemist looking to take on a leadership role in a dynamic team? We are seeking a highly skilled Director of Bioconjugate Chemistry to join our Discovery Chemistry team in South San Francisco, CA.Key ResponsibilitiesLeverage your expertise in medicinal chemistry to lead high-impact research projects in bioconjugates...
-
Senior Director of Analytical Chemistry
2 weeks ago
San Francisco, California, United States IDEAYA Biosciences Full timeAbout IDEAYA BiosciencesIDEAYA Biosciences is a clinical-stage precision medicine oncology company committed to the discovery and development of targeted therapeutics for patient populations selected using DNA sequencing and other molecular diagnostics.We integrate extensive capabilities in identifying and validating translational biomarkers with small...
-
Associate Director, CMC Analytical Chemistry
2 weeks ago
San Francisco, California, United States Cytokinetics Full timeAbout the RoleCytokinetics is a leading biopharmaceutical company focused on developing innovative treatments for cardiovascular diseases. We are seeking an experienced Associate Director to join our team in a key leadership role.Job SummaryThe Associate Director will be responsible for leading our analytical development activities, providing technical...
-
San Francisco, California, United States IDEAYA Biosciences Full timeAbout IDEAYA BiosciencesIDEAYA Biosciences is a clinical-stage precision medicine oncology company dedicated to the discovery and development of targeted therapeutics for patient populations selected using DNA sequencing and other molecular diagnostics.Job SummaryWe are seeking an experienced and highly motivated Associate Director/Director, Head of...
-
Executive Director of Biostatistics
2 weeks ago
South San Francisco, California, United States People With Chemistry Full timeJob Title: Executive Director, BiostatisticsAt People With Chemistry, we are seeking an experienced Executive Director to lead our Biostatistics team. As a key member of our Biometrics function, you will provide strategic leadership and oversight of biostatistical deliverables to support our growing portfolio of clinical development programs.Key...
-
San Francisco, California, United States Genentech Full timeJob SummaryWe are seeking a highly motivated and talented Process Engineer I Chemistry Small Molecule Process to join our Department of Small Molecule Process Chemistry at Genentech.The successful candidate will work with our South San Francisco process development team, participating in the development of early phase GMP chemical manufacturing processes.Key...
-
San Francisco, California, United States Genentech Full timeJob SummaryWe are seeking a highly motivated and talented Process Engineer I Chemistry Small Molecule Process to join our Department of Small Molecule Process Chemistry at Genentech. The successful candidate will work with our South San Francisco process development team to develop early phase GMP chemical manufacturing processes.Key Responsibilities Conduct...
-
Associate Director, CMC Analytical Chemistry
4 weeks ago
South San Francisco, California, United States Cytokinetics Full timeJob SummaryCytokinetics is a pioneering biopharmaceutical company dedicated to developing innovative treatments for cardiovascular diseases. As an Associate Director, CMC Analytical Chemistry, you will play a crucial role in leading our analytical development efforts, ensuring the quality and safety of our products.Key ResponsibilitiesLead and manage...
-
South San Francisco, California, United States Genentech Full timeJob Title: Process Engineer I Chemistry Small Molecule ProcessWe are seeking a highly motivated and talented Process Engineer I to join our Department of Small Molecule Process Chemistry at Genentech. As a key member of our team, you will be responsible for developing early phase GMP chemical manufacturing processes and maintaining a high-level scientific...
-
South San Francisco, California, United States IDEAYA Biosciences Full timeJob Title: Associate Director/Director, Head of Discovery Analytical ChemistryIDEAYA Biosciences is a leading precision medicine oncology company committed to the discovery and development of targeted therapeutics. We are seeking an experienced Associate Director/Director, Head of Discovery Analytical Chemistry to join our multidisciplinary team based in...
-
Associate Director, CMC Analytical Chemistry
2 weeks ago
South San Francisco, California, United States Cytokinetics Full timeJob SummaryCytokinetics is a pioneering biopharmaceutical company dedicated to advancing muscle biology and mechanics. As a leader in the field, we are seeking an experienced Associate Director to join our CMC Analytical Chemistry team.Key ResponsibilitiesLead and track Analytical Development activities for pipeline productsProvide analytical support for...
-
Associate Director, CMC Analytical Chemistry
4 days ago
South San Francisco, California, United States Cytokinetics Full timeCytokinetics: A Leader in Muscle Biology and Cardiac Muscle PerformanceCytokinetics is a late-stage, specialty cardiovascular biopharmaceutical company dedicated to discovering, developing, and commercializing innovative muscle activators and inhibitors as potential treatments for debilitating diseases affecting cardiac muscle performance. With a strong...
-
San Francisco, California, United States IDEAYA Biosciences Full timeJob SummaryWe are seeking an experienced and highly motivated Associate Director/Director, Analytical Chemistry to join our multidisciplinary team based in South San Francisco. The role requires the candidate to work collaboratively with the related cross-functional teams to support our drug discovery pipeline.Key ResponsibilitiesLead the analytical...
-
San Francisco, California, United States Johnson Service Group Full timeJob OverviewJohnson Service Group is seeking a highly skilled Director of Peptide Chemistry Research and Development to lead our Peptide Research Department. The successful candidate will oversee peptide design, synthesis, and research projects, collaborating with global teams and clients to drive innovative solutions in peptide drug discovery.**Key...
