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Senior Principal Scientist
2 months ago
Bristol-Myers Squibb is seeking a highly skilled Senior Principal Scientist to join our Translational Medicine team in Neurology. As a key member of our team, you will be responsible for leading translational and clinical biomarker activities to support drug development programs in multiple diseases in neurology and neuropsychiatry.
Key Responsibilities- Design and implement program-specific biomarker/translational plans, responsible for aiding in creation of clinical protocols, SAPs, SOWs, lab manual, and interfacing with CRO for execution of services, in conjunction with Biospecimen Operations and Procurement.
- Determine appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicable.
- Manages clinical biomarker data delivery and analysis and associated timelines by working with relevant internal functions and CROs.
- Prepares and delivers internal and external translational/biomarker presentations.
- Maintains timelines for biomarker data related publication through interaction with Medical Communications and Publication team as needed.
- Keeps up-to-date on relevant scientific/technical literature in order to applying external knowledge to internal research programs as appropriate and acts as a subject-matter expert within the team to critically evaluate the literature regarding the asset and disease biology.
- Works with TM laboratory scientists and academic TLs to address nonclinical translational questions.
- Participates in post-hoc biomarker analysis and publication efforts.
- Supports regulatory submissions and regulatory interactions as needed.
- Understanding of late stage drug development.
- Experience in activities required for and related to clinical trial initiation, maintenance and completion.
- Experience in interacting with CROs and TLs to manage projects and timelines.
- Proven scientific/leadership expertise (working in teams, mentoring people, managing projects).
- Accountable for timelines and deliverables.
- Prioritizes risks and implements contingency plans.
- Communicates regularly; prepares and delivers presentations within the department, to governance and senior leadership bodies, and externally as requested.
- Recognizes cross-functional issues and communicates within the larger organization.
- Provides expert guidance to multi-disciplinary teams and senior management.
- Has a track record of delivering results, driving continuous improvements, and building effective cross-functional networks.
- Ability to prioritize and manage time efficiently.
- Strong verbal and written communication skills.
- Accurate and detailed record keeping.
- Excellent organizational skills.
- Ph.D. in neuroscience or related field 8+ years of academic/biotech experience.
- Minimum 3 years of clinical biomarker experience.
