Pediatric Hematology Oncology Research Scientist

2 weeks ago


Pasadena, Texas, United States InsideHigherEd Full time
Pediatric Hematology Oncology Project Scientist

We are seeking a highly motivated Project Scientist to join our interdisciplinary research team in the Department of Pediatrics at the University of California, Los Angeles. The successful candidate will be responsible for conducting research in the area of pediatric hematology oncology, with a focus on developing new nanotechnology-enabled methods to support the childhood cancer and regenerative medicine research communities.

Key Responsibilities:
  • Establish rapid, safe, cost-effective, and efficient intracellular delivery methods for genes and genome-editing machinery.
  • Design and apply nanocarrier systems to enable cystic fibrosis gene therapies.
  • Develop microfluidic liquid biopsy technologies for monitoring treatment response to pediatric sarcomas and other childhood malignancies.
  • Apply rapid prototyping approaches to fabricate three-dimensionally printed tools for organoid development & toxicity screening of electronic cigarette/vaping products.
Qualifications:
  • PhD, MD/PhD, or equivalent in Bioengineering, Materials Science, Chemistry, Mechanical Engineering, Physics, Electrical Engineering, Molecular Biology or related life science fields of study.
  • Background in nanoparticle synthesis & characterization and mRNA therapeutics.
  • Solid understanding and experience in micro/nanofabrication techniques, microfluidic devices, three-dimensional printing, device design and characterization.
  • Experience in cell culture, cell biology & molecular biology, immunofluorescence/flow cytometry, next generation sequencing techniques, gene editing methods, and biochemical techniques desired.
  • Ability to multitask and quickly adapt to new research challenges.
  • Excellent communication skills and ability to work in a diverse, interdisciplinary research environment and to interact with computational and experimental scientists.
Skills:
  • Experience with micro/nanofabrication techniques, including photolithography and three-dimensional printing for rapid prototyping and application of microfluidic systems.
  • Experience in the design of computer models/simulations for prototyping of project-specific devices.
  • Experience in nanoparticle synthesis and characterization (e.g., lipid nanoparticles, polymeric, plasmonic nanomaterials).
  • Experience with cell culture, transfection, immunofluorescence/flow cytometry, and biochemical and molecular biology techniques.
  • Comfortable working with human primary cell types including hematopoietic stem cells, immune cells, or pluripotent stem cells.
Duties and Responsibilities:
  • Ability to work and lead more independently and multitask projects more extensively.
  • Leadership and coordination of project activities and collaborative efforts.
  • Oversee development of technology platforms for cellular therapy manufacturing, nanoparticle vehicles, organoids, and/or liquid biopsy diagnostic tests and characterization of cell products resulting from this work.
  • Ability to multitask and contribute to and oversee multiple collaborative projects efficiently and effectively.
  • Supervision, mentorship, and teaching of undergraduate, graduate, and medical students, new postdoctoral trainees, and staff research associates in the lab.

We are an equal opportunity employer and welcome applications from diverse candidates. The University of California is committed to diversity, equity, and inclusion and is an affirmative action/equal opportunity employer. For more information, please visit our website at https://www.ucla.edu/.



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