Oligonucleotide Production Scientist
2 weeks ago
POSITION OVERVIEW
The Oligonucleotide Production Scientist plays a pivotal role in the research scale-up and manufacturing processes, utilizing scientific expertise to facilitate the seamless transition of innovative products from development to production. Responsibilities include the post-labeling of oligonucleotides using various chemistries.
This position requires a full-time, onsite commitment.
KEY RESPONSIBILITIES
- Manage oligonucleotide production, including the operation of automated synthesis machinery (ABI and AKTA 10 & 100).
- Post-label oligonucleotides with diverse chemistries.
- Complete all necessary training for Oligo Mixing, instrument operation, and essential oligo production tasks, adhering to regulatory standards.
- Utilize analytical instruments such as HPLC, UHPLC, LC-MS, UV-Vis, and fluorescence spectroscopy, while also employing other methods for reagent characterization.
- Process production materials through bench techniques and laboratory instruments (Prep HPLC, pH probes, balances, NanoDrop, and rotary evaporators).
- Oversee batch production, prepare protocols, and revise process procedures in compliance with ISO-9001 quality standards.
- Maintain an inventory of raw materials and final products.
- Exhibit strong production skills while adhering to safe laboratory practices and environmental regulations.
- Collaborate effectively with team members to enhance production efficiency and meet project deadlines.
- Perform additional duties as required.
Ideal candidates will possess:
- A BS/MS degree in Chemistry, Biology, or a related discipline.
- A minimum of 3-5 years of experience in the life sciences sector.
- Proficiency with automated synthesis equipment (ABI and AKTA 10 & 100) and purification instruments is essential.
- Strong logical thinking, task prioritization, self-motivation, and effective teamwork abilities.
- Excellent verbal and written communication skills.
- In-depth knowledge of synthetic chemistry and scale-up processes is highly desirable.
- Strong communication skills for interacting with supervisors, instructing junior staff, and collaborating across departments.
BENEFITS:
Our comprehensive benefits program supports the physical, emotional, and financial well-being of our employees and their families.
What we provide:
- Extensive medical, dental, and vision coverage, including options for spouses/domestic partners and dependents, along with access to Health Savings Accounts (HSA) and Flexible Spending Accounts (FSA).
- Employee assistance programs and comprehensive behavioral health benefits.
- Fertility support, including surrogacy and adoption assistance.
- Life insurance options for employees and their families.
- Voluntary benefits such as group legal services and identity theft protection.
- Short-term and long-term disability plans.
- Paid parental and caregiver leave.
- 401(k) Plan with various options and immediate company matching.
- Education assistance and student loan programs.
- Generous time off policies, including vacation, paid holidays, and special leave programs.
- Referral bonuses for eligible employees.
- Matching gift initiatives.
- A variety of employee business resource groups (EBRGs).
- Exclusive discounts on Sony products for employees.
- Employee stock purchase plans with covered commissions and fees.
- Annual incentive bonuses.
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