Senior Associate Scientist, Oncology Research and Development

2 weeks ago

Foster City, United States GILEAD Sciences Full time
Job Description

Gilead Sciences is seeking a talented and highly motivated scientist to join our oncology research group. Our collaborative and interdisciplinary research team utilizes state-of-the-art technologies and innovative methodologies to advance medicines into the clinic.

Key Responsibilities
  • Independently plan, execute, analyze, troubleshoot, and interpret in vitro and ex vivo experiments that support non-routine research activities and projects goals
  • Proactively evaluate new technologies and develop new assays to accelerate early-stage discovery activities and/or enhance our understanding of disease mechanisms
  • Support multiple projects simultaneously and work cross-functionally with colleagues in the oncology, chemistry, protein engineering, pathobiology, DMPK, biomarker, and clinical groups
  • Present research findings and recommendations to senior staff and contribute to preparation of research reports, manuscripts, INDs, and patent filings
  • Provide coaching and training to junior and/or less experienced colleagues in solving technical and scientific problems
Requirements
  • Master's degree and 8+ years of experience or Bachelor's degree and 10+ years of experience in cell biology, molecular biology, or biochemistry in biotechnology or pharmaceutical industry
  • Extensive experience in cancer cell biology, target identification/validation in oncology or immuno-oncology
  • Experience working with small molecules
  • Extensive experience in general molecular and cell biology methods including primary human and mouse cell culture and basic flow cytometry
  • High proficiency in techniques evaluating cell signaling (e.g. western blot, ELISA, MSD, immunofluorescence, reporter-based assays) and proliferation / survival using small-molecules and biologics
  • Proficiency in methods evaluating gene expression (e.g. RT-qPCR, Nanostring and others)
  • Experience with methods to perturb gene function (e.g. RNAi, CRISPR, overexpression) and to deliver constructs (e.g. transfection, electroporation, lentiviral transduction)
  • Experience with quantitative cellular assays
Preferred Skills
  • Expertise in cell cycle analysis and high content imaging
  • A strong record of achievements, contributions to drug discovery programs, and publications
Compensation and Benefits

The salary range for this position is: $133,280.00 - $172,480.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*. For additional benefits information, visit: * Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

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