Research Scientist

4 weeks ago

Worcester, Massachusetts, United States UMass Med School Full time
Job Title: Sr Research ScientistJob Summary:

We are seeking a highly motivated and experienced Sr Research Scientist to join our team at the UMass Med School. The successful candidate will be responsible for conducting and evaluating scientific research in a laboratory setting, with a focus on metabolomics and lipidomics.

Key Responsibilities:
  • Conduct complex tests, experiments, and procedures following established protocols
  • Apply and interpret theoretical knowledge to conduct research in one or more scientific disciplines
  • Identify potential problems, recommend solutions, and collaborate in the development of new techniques
  • Monitor and collect data as required by research protocols
  • Maintain accurate documentation of research results
  • Search literature to assist in the design of methods, procedures, and techniques
  • Configure, operate, and maintain specialized equipment
  • Use software applications to assemble, manipulate, format, and perform statistical analysis of data
  • Assist in writing grants, progress reports, and manuscripts
  • Prepare samples for metabolomics and lipidomics experiments
  • Optimize extraction protocols
  • Perform LC/MS/MS experiments for targeted and untargeted metabolomics and lipidomics
  • Perform data analysis using software such as TraceFinder, Compound Discoverer, and LipidSearch
  • Consult with researchers on experimental design and data interpretation
  • Produce reports and share them with collaborators
  • Participate in grant writing and manuscript preparation
  • Present data at group meetings
  • Operate, maintain, and troubleshoot a variety of mass spectrometers
  • Develop new metabolomics and lipidomics methods and workflows as needed
  • Assist with general laboratory tasks as needed
  • Maintain detailed records and adhere to SOPs
  • Supervise and train new laboratory personnel and junior members of the laboratory
Requirements:
  • Ph.D. and 1 year of postdoctoral experience in analytical chemistry, biochemistry, or equivalent
  • 7 years of research experience, including 3 years of experience in metabolomics
  • Familiarity with high-resolution mass spectrometers
  • Experience with liquid-chromatography
  • Willingness to work in a collaborative environment with an outgoing customer service acumen
  • Recent bench work experience required
  • Ability to prepare research reports
  • Good verbal and written communication skills
  • Demonstrated ability to understand scientific, experimental, and research theory
Preferred Qualifications:
  • Experience with lipidomics strongly preferred
  • Experience with gas-chromatography
  • An understanding of the use of stable isotopes in tracing experiments
  • A broad knowledge of open-source, high-resolution, accurate-mass data analysis software
  • Experience in advanced data processing and analysis encouraged (use of Matlab, R, Python, etc.)
  • Familiarity with statistical methods used in larger cohort studies

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