Research Scientist
5 days ago
We are seeking a highly motivated and experienced Sr Research Scientist to join our team at the UMass Med School. The successful candidate will be responsible for conducting and evaluating scientific research in a laboratory setting, with a focus on metabolomics and lipidomics.
Key Responsibilities:- Conduct complex tests, experiments, and procedures following established protocols
- Apply and interpret theoretical knowledge to conduct research in one or more scientific disciplines
- Identify potential problems, recommend solutions, and collaborate in the development of new techniques
- Monitor and collect data as required by research protocols
- Maintain accurate documentation of research results
- Search literature to assist in the design of methods, procedures, and techniques
- Configure, operate, and maintain specialized equipment
- Use software applications to assemble, manipulate, format, and perform statistical analysis of data
- Assist in writing grants, progress reports, and manuscripts
- Prepare samples for metabolomics and lipidomics experiments
- Optimize extraction protocols
- Perform LC/MS/MS experiments for targeted and untargeted metabolomics and lipidomics
- Perform data analysis using software such as TraceFinder, Compound Discoverer, and LipidSearch
- Consult with researchers on experimental design and data interpretation
- Produce reports and share them with collaborators
- Participate in grant writing and manuscript preparation
- Present data at group meetings
- Operate, maintain, and troubleshoot a variety of mass spectrometers
- Develop new metabolomics and lipidomics methods and workflows as needed
- Assist with general laboratory tasks as needed
- Maintain detailed records and adhere to SOPs
- Supervise and train new laboratory personnel and junior members of the laboratory
- Ph.D. and 1 year of postdoctoral experience in analytical chemistry, biochemistry, or equivalent
- 7 years of research experience, including 3 years of experience in metabolomics
- Familiarity with high-resolution mass spectrometers
- Experience with liquid-chromatography
- Willingness to work in a collaborative environment with an outgoing customer service acumen
- Recent bench work experience required
- Ability to prepare research reports
- Good verbal and written communication skills
- Demonstrated ability to understand scientific, experimental, and research theory
- Experience with lipidomics strongly preferred
- Experience with gas-chromatography
- An understanding of the use of stable isotopes in tracing experiments
- A broad knowledge of open-source, high-resolution, accurate-mass data analysis software
- Experience in advanced data processing and analysis encouraged (use of Matlab, R, Python, etc.)
- Familiarity with statistical methods used in larger cohort studies
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