Scientist I

4 weeks ago


Chicago, Illinois, United States Collabera Full time
Job Title: Scientist I - CRISPR/Cas Researcher

Job Summary:
Collabera is seeking a highly motivated Scientist I - CRISPR/Cas Researcher to join our team. The successful candidate will be responsible for performing routine cell culture work, performing differentiation of induced pluripotent stem cells (iPSCs), and participating in cross-functional target identification and validation projects.

Key Responsibilities:
  • Perform routine cell culture work to maintain and expand cell lines, including iPSCs.
  • Perform differentiation of iPSCs towards cell types of interest (e.g. retinal cells, immune cells).
  • Perform CRISPR/Cas functional genomics research based on lentiviral and RNP delivery methods.
  • Participate in cross-functional target identification and validation projects to support early drug discovery efforts in immunology and ophthalmology.
  • Develop cell-based functional assays relevant to disease biology.
  • Perform arrayed and pooled CRISPR screens using fluorescent cell sorting and high content imaging assays.
  • Collaborate extensively with scientists across diverse functional and therapeutic areas in a matrixed research environment.
  • Communicate and present project designs and results clearly, both to individual stakeholders and in group settings.

Qualifications:
  • BS, MS, and/or PhD in Immunology, Molecular Biology, Cell Biology, Biomedical Engineering, or in a related discipline.
  • BS with 5+ years' experience in a lab setting, MS with 2+ years, or PhD with 0+ years' experience in a lab setting, either within an industry and/or academic setting.
  • Experience with in vitro cell culture, aseptic technique, and development of cell-based assays is required, minimum 1 year.
  • Experience in flow cytometry, immunofluorescence, and/or protein assays (e.g. ELISA, Western Blot) is expected, minimum 1 year.
  • Experience in transfection, nucleofection, and viral transduction is a plus.
  • Experience within immunology, neuroscience, and/or ophthalmology research is a plus.
  • Knowledge or Experience in CRISPR systems is a plus.
  • Ability to learn new skills and apply them in a fast-paced research environment is a must.
  • Creativity, problem-solving, organizational skills, and attention to details are expected.
  • Strong communication and collaboration skills are essential.
  • Ability to work independently as well as in a team is a must.

What We Offer:
  • A dynamic and collaborative research environment.
  • Opportunities for professional growth and development.
  • A competitive salary and benefits package.

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