Clinical Science Director

6 hours ago

San Francisco, California, United States Nurix, Inc. Full time

Job Summary:

We are seeking a highly skilled Clinical Science Director to join our Clinical Development Team. This individual will work closely with study teams to provide scientific guidance and support.

The successful candidate will report to the VP, Head of Clinical Science or a more senior member of the Clinical Science team.

This role will contribute to the strategy to advance molecules through the Nurix clinical pipeline. The Clinical Science Director will work cross-functionally and participate in the execution of clinical studies, including protocols, provide scientific expertise to support site and CRA training, data cleaning/analysis, investigator interaction, and support of regulatory filings.

In collaboration with the Medical Monitor and Safety team, this role will be responsible for safety oversight of clinical trials.

Responsibilities:

Participate in cross-functional clinical development teams with strong ability to work closely with all team members, address study or other program-specific questions.

Implement Global Development Plan with strategic clinical science support.

Author and/or review clinical protocols.

Read and interpret scientific and medical literature for use in clinical documents and to assist clinical team decision making.

Prepare clinical portions of all relevant regulatory filings and meeting packages (INDs, Annual Reports, meeting requests, NDAs, etc.) for US and ex-US Health Authorities as needed.

Integrate scientific knowledge and operational expertise to ensure translation of clinical research plans into efficiently delivered high-quality studies.

Acquire and utilize knowledge of clinical trial design and relevant disease indications to assist in study concept and protocol development.

Contribute to discussions concerning scientific and procedural aspects of study design.

Coordinate with departments to produce the final protocol and informed consent documents.

Contribute and review medical data review plans, Data Safety Monitoring Board (DSMB)/Safety Review Committee (SRC) charters, and specific sections of study manuals and investigator meeting materials.

Contribute to the development of CRFs, data edit checks, and/or patient profile design.

Conduct ongoing data cleaning (query generation, coding review, SAE reconciliation) and data trend analysis.

Lead internal clinical data review meetings in conjunction with the medical monitor, if applicable.

Prepare slides as needed for site calls and for dose escalation meetings, as applicable to study stage.

Coordinate with Medical Affairs and manage external medical advisory committees for the study team, such as DSMBs and Scientific Steering Committees, in conjunction with the medical monitor.

Research and summarize published literature for continual learning and to prepare training materials for other clinical team members.

Contribute to statistical analysis plans, table, listing, figure design, and the preparation of manuscripts and other presentations of study data, as appropriate.

Address investigator questions regarding protocol and related scientific issues and attend site initiation visits (SIVs), in coordination with the medical monitor.

Assist in determining the activities to support a project's priorities within functional area.

Up to 25% travel (US and International).

Basic Qualifications:

Advanced degree in clinical or biological sciences (MD, PhD, or PharmD preferred) and 4+ year's (Associate Dir) or 8+ years (Director) relevant drug development experience with minimum of 3 years' experience in oncology clinical trials.

Preferred Qualifications:

Experience in the clinical science role, in an oncology indication for first-in-human and proof of concept studies in small molecules, biologics, and/or cell therapy.

Registrational or Phase 3 study experience is desired.

In-depth understanding of clinical operations and translational medicine.

Excellent interpersonal and communication skills.

Able to translate technical concepts into accessible language and direction for the broader study team.

Excellent attention to detail, collaboration, and initiative, with flexibility to adapt to the needs of the organization; maintain meticulous attention to project deadlines.

Experienced in Microsoft Office (Excel, Word, PowerPoint, OneNote), and ideally also with job-related programs such as Spotfire and Medidata Rave or similar.

Strong understanding of ICH GCP, as well as general knowledge of industry practices and standards.

Commitment to patient safety and clinical compliance.

  • Clinical Science Director

    1 month ago

    San Francisco, California, United States Meet Full time

    Director, Clinical ScienceWe are seeking a highly experienced Director, Clinical Science to lead our early-phase oncology project in car T-cell therapy. This is a long-term, fully remote consultancy role requiring 40 hours of work per week.Key Responsibilities:Develop and execute clinical development strategies for oncology projectsLead cross-functional...

  • Director of Clinical Science

    3 weeks ago

    San Francisco, California, United States Meet Full time

    Director, Clinical ScienceWe are seeking a highly experienced Director, Clinical Science to lead our early-phase oncology, CAR-T cell therapy project. This is a 40-hour per week, fully remote consultancy role that requires full-time hours.Key Responsibilities:Lead clinical development efforts for early-phase oncology projectsDevelop and implement clinical...

  • Clinical Science Director

    2 weeks ago

    San Francisco, California, United States Nurix, Inc. Full time

    Job Summary:Nurix Therapeutics, Inc. is seeking a highly skilled and experienced Clinical Science Director to join our Clinical Development Team. As an integral member of the team, you will work closely with study teams to provide scientific guidance and support.The successful candidate will report to the VP, Head of Clinical Science or a more senior member...

  • Clinical Science Director

    3 days ago

    San Francisco, California, United States Nurix, Inc. Full time

    Job Summary:As a key member of the Clinical Development Team at Nurix Therapeutics, Inc., this role will collaborate closely with study teams to provide scientific guidance and support. The Associate Director/Director, Clinical Science will report to the VP, Head of Clinical Science or a senior member of the Clinical Science team. This individual will...

  • Clinical Science Director

    4 weeks ago

    San Francisco, California, United States Daiichi Sankyo, Inc. Full time

    Director, Clinical Science, ENHERTUAbout the RoleWe are seeking a highly skilled and experienced Director, Clinical Science to lead our clinical development efforts for ENHERTU, a novel therapy in oncology. As a key member of our team, you will be responsible for overseeing the design, execution, and delivery of clinical trials, ensuring the highest quality...

  • Clinical Science Director

    2 weeks ago

    San Francisco, California, United States Nurix, Inc. Full time

    Job Summary:Nurix Therapeutics, Inc. is seeking a highly skilled and experienced Clinical Science Director to join our Clinical Development Team. As an integral member of the team, you will work closely with study teams to provide scientific guidance and support. The successful candidate will report to the VP, Head of Clinical Science or a more senior member...

  • Senior Clinical Science Director

    2 days ago

    San Francisco, California, United States BioSpace, Inc. Full time

    Job Title: Senior/Executive Director, Clinical ScienceAs a key member of the Clinical Development Team, this role will collaborate closely with study teams to provide scientific guidance and support. The Senior/Executive Director, Clinical Science will report to the VP, Head of Clinical Science and be responsible for developing and contributing to the...

  • Senior Director of Clinical Science

    4 days ago

    San Francisco, California, United States Nurix, Inc. Full time

    Job Title: Senior/Executive Director, Clinical ScienceAs a key member of the Clinical Development Team at Nurix Therapeutics, Inc., this role will play a critical part in advancing molecules through our clinical pipeline. The Senior/Executive Director, Clinical Science will report to the VP, Head of Clinical Science and be responsible for developing and...

  • Clinical Science Director

    3 weeks ago

    San Francisco, California, United States Nurix, Inc. Full time

    Job SummaryWe are seeking a highly skilled and experienced Clinical Science Director to join our Clinical Development Team. As an integral member of the team, you will work closely with study teams to provide scientific guidance and support.Key ResponsibilitiesContribute to the development of clinical strategies to advance molecules through our pipeline.Work...

  • Senior Director of Clinical Science

    4 days ago

    San Francisco, California, United States BioSpace, Inc. Full time

    Job SummaryWe are seeking a highly experienced Senior/Executive Director, Clinical Science to join our Clinical Development Team. This individual will work closely with study teams to provide scientific guidance and support, and will be responsible for developing and contributing to the strategy to advance molecules through our clinical pipeline.Key...

  • Director, Clinical Science

    10 hours ago

    South San Francisco, California, United States Zai Lab (US) LLC Full time

    Job SummaryZai Lab (US) LLC is seeking a highly skilled Director, Clinical Science to join our team in South San Francisco, CA. As a key member of our clinical research team, you will be responsible for driving the scientific rigor and integrity of our clinical research.The ideal candidate will have a strong background in clinical research, with a minimum of...

  • Clinical Science Director

    2 weeks ago

    San Diego, California, United States Xencor Full time

    Job Title: Clinical Science DirectorXencor is a leading biopharmaceutical company dedicated to developing innovative treatments for patients with cancer and other serious diseases. We are seeking a highly skilled Clinical Science Director to join our team in San Diego, CA.Job Summary:The Clinical Science Director will be responsible for facilitating the...

  • Associate Director Clinical Science

    4 weeks ago

    San Francisco, California, United States Daiichi Sankyo, Inc. Full time

    About Daiichi Sankyo, Inc.Daiichi Sankyo, Inc. is a global pharmaceutical innovator dedicated to creating and supplying innovative therapies to improve standards of care and address unmet medical needs. With a rich legacy of innovation and a robust pipeline of promising new medicines, we are committed to delivering value to our stakeholders and making a...

  • Director of Diagnostic Sciences

    4 weeks ago

    San Francisco, California, United States Daiichi Sankyo, Inc. Full time

    Director, Diagnostic Sciences, Global Companion DiagnosticsAbout the RoleWe are seeking a highly skilled and experienced Director, Diagnostic Sciences to join our Global Companion Diagnostics team at Daiichi Sankyo, Inc. This is an exciting opportunity to lead the end-to-end process for CDx implementation in clinical studies, ensuring that sample testing and...

  • Clinical Science Director

    3 weeks ago

    San Mateo, California, United States BeiGene Full time

    Job Title: Associate Director, Clinical ScienceJob Summary:The Associate Director, Clinical Science will play a key role in supporting BeiGene's Clinical and Medical assets by successfully executing clinical development programs and deliverables in partnership across the organization, with external vendors, and with external academicians and collaboration...

  • Director of Diagnostic Sciences

    3 days ago

    San Francisco, California, United States Daiichi Sankyo, Inc. Full time

    Unlock a Legacy of InnovationDaiichi Sankyo Group is dedicated to creating and supplying innovative pharmaceutical therapies to improve healthcare standards and address unmet medical needs globally. With a rich legacy of innovation and a robust pipeline of promising new medicines, we strive to make a meaningful difference in people's lives. Our focus on...

  • Data Science Director

    1 week ago

    San Francisco, California, United States Blockchain Technologies Corp. Full time

    Job Title: Director of Data ScienceWe are seeking a highly skilled Director of Data Science to join our team at Blockchain Technologies Corp. in San Francisco.The ideal candidate will be a proven leader with deep analysis and programming skills, and an exemplary understanding of statistics and hypothesis testing.The Director of Data Science will be...

  • Data Science Director

    2 weeks ago

    San Francisco, California, United States ETHEREUM TECHNOLOGIES LLC Full time

    Job Title: Director of Data ScienceWe are seeking a highly skilled and experienced Director of Data Science to lead our data science team and drive business growth through data-driven decision making.The ideal candidate will have a strong background in data science, machine learning, and statistics, with experience in leading high-performing teams and...

  • Clinical Science Director

    2 days ago

    San Mateo, California, United States BeiGene Full time

    Job Summary:The Associate Director – Clinical Science will play a key role in the establishment and growth of Clinical Research functions at BeiGene, ensuring best-in-class global capabilities and execution. This position will support the successful execution of clinical development programs and deliverables in partnership across the organization, with...

  • Data Science Director

    1 week ago

    San Francisco, California, United States Cisco Full time

    About the RoleCisco Meraki is seeking a seasoned Data Science Director to lead our growing team of data scientists, machine learning engineers, and data analysts. As a key member of our executive team, you will be responsible for developing and implementing data-driven strategies to drive business growth and improve customer experience.Key...