Associate Director Translational Biomarker Lead Inflammation/Autoimmune Disease, ECD TAU
15 hours ago
Takeda is a global pharmaceutical company committed to transforming patient care through the development of novel specialty pharmaceuticals and best-in-class patient support programs.
We are seeking an experienced Associate Director to lead our Translational Biomarker Research team in the Inflammation/Autoimmune Disease area.
The successful candidate will provide scientific and strategic leadership in developing the translational biomarker strategy, and plans to secure implementation for Inflammation and Autoimmune (AI) diseases programs in clinical and pre-clinical stages of development.
This is a highly visible, strategic, and matrixed role, responsible for leading the Translational subteam (TST) partnering with Gastro-Intestinal drug discovery unit (GI-DDU) discovery research and physician-scientists and relevant partner lines and functions to identify and validate biomarkers relevant to patients in clinical studies.
Key Responsibilities:
- Develop and execute translational biomarker strategy and plans as part of the overall Asset Strategy in the Discovery and Global Product Teams through all stages of clinical development and post-market activities.
- Secure implementation and delivery of data.
- Partner with GI-DDU discovery research and physician-scientists in designing and executing Translational Research to discover and validate targeted pathways based on human data and define candidate biomarkers for mechanisms of action and drug response.
- Lead Translational Biomarker strategy development and execution to support the clinical stage portfolio, including biomarker-driven clinical study design, implementation of novel technologies, and incorporation of biomarker endpoints for decision-making in early-stage clinical trials.
- Represent Translational and Biomarker Research on Project and Global Product Teams to provide pharmacodynamic, disease and predictive biomarker strategies and support translational medicine goals of the assigned programs in all phases of clinical development.
Requirements:
- PhD or MD/PhD degree in a scientific discipline with 8+ years experience, or MS with 16+ years experience, or BS with 18+ years experience.
- At least 5 years of experience in clinical translational biomarker research.
- Outstanding expertise and depth of knowledge within Inflammation and Autoimmune diseases clinical translational and biomarker space. Dermatology, gastroenterology and/or rheumatology experience preferred.
- Recognized expertise in biomarker discovery and development and Translational Medicine as demonstrated by publications, regulatory submissions, and/or national or international presentations.
- Excellent understanding of drug development, regulatory processes, and clinical development.
- Strong leadership abilities and proven ability to lead a team within a matrix organization as well as work independently.
- Strong analytical, oral, and written communication, problem-solving, and interpersonal skills.
Takeda is an equal opportunity employer and welcomes applications from diverse candidates. We are committed to creating a diverse and inclusive workplace that reflects the communities we serve.
Location: Boston, MA
Job Type: Full-time
Salary Range: $149,000 - $234,300 per year
Benefits: Medical, dental, vision insurance, 401(k) plan, company match, short-term and long-term disability coverage, basic life insurance, tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits.
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