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Principal Scientist

2 months ago


Torrance, California, United States Sakura Finetek USA Full time
Job Summary

We are seeking a highly skilled and experienced Senior Research Scientist to join our team at Sakura Finetek USA. The successful candidate will be responsible for leading the development of new reagents and assays for automated and manual immunohistochemistry (IHC) and in situ hybridization (ISH) staining.

Key Responsibilities
  • Research and Development:
    • Develop high-quality reagents and IHC or ISH staining protocols to meet the demands of our global IHC and ISH market.
    • Design and develop new antibodies, probes, and IHC/ISH detection reagents to expand our reagent lines, documenting appropriate specificity/sensitivity, precision, robustness, and stability as required.
    • Continuously monitor productivity and quality and implement improvements.
    • Facilitate technology and reagent development process transfers.
    • Support program directives from senior management.
  • Quality and Business Systems:
    • Ensure that our Quality System is deployed and actively seek continuous improvement opportunities.
    • Adhere to Good Laboratory Practice (GLP) and support any activity that is needed for FDA and IVDR compliance and/or ISO certification.
    • Follow up on R&D action items addressed by different teams and assist in resolving quality issues.
    • Implement preventive action based on improvement opportunities or trends identified during Leadership Review meetings.
  • Essential Requirements:
    • Ph.D. or master's degree or equivalent in a relevant scientific discipline.
    • Experience in tissue histology or pathology.
    • Theoretical knowledge of antibodies, immunohistochemistry, various antibody conjugation, immunology, histology, pathology, and molecular biology.
  • Desirable Skills:
    • Minimum of five years of laboratory experience, including independent experimental design, data collection, interpretation, and report writing.
    • Demonstrated expertise with histology and anatomic pathology methods, including IHC/ISH staining and microscopic interpretation of stained slides.
    • Proficient in immunohistochemistry and in-situ hybridization methodologies on formalin-fixed, paraffin-embedded human tissues.
    • Ability to troubleshoot assay performance issues independently.
    • Excellent analytical, organizational, and problem-solving abilities.
    • Proven capability to lead and coordinate teams to reach targets and assess the success of various programs and projects.
  • Working Environment:
    • This position requires the employee to sit and work in a laboratory setting frequently.
    • Occasional travel may be required.