Senior Research Scientist, Ophthalmology Discovery

4 weeks ago


Irvine, California, United States AbbVie Full time

About the Role

Absorb the opportunity to contribute to AbbVie's mission to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow.

We are seeking a highly motivated and experienced Principal Research Scientist II to join our Ophthalmology Discovery group.

As a key member of our team, you will be responsible for the design and implementation of pre-clinical in vivo studies to identify, validate, and characterize potential therapeutic targets and assets to support ophthalmic drug discovery and development programs.

Key Responsibilities

  • Lead and contribute to the implementation of strategies for the discovery and validation of targets in ophthalmology.
  • Develop and implement innovative translatable large animal models of retinal and optic nerve diseases with clinically relevant endpoints.
  • Lead a team that generates disease models using surgical, laser, drug, chemical, or genetic techniques and select and optimize appropriate endpoints.
  • Collect and analyze data, interpret results, and report on nonclinical in vivo pharmacology studies.
  • Collaborate with peers in multidiscipline programs or project teams and advise and consult with other scientists in R&D as well as outside collaborators.

Requirements

  • 8 years of pharmaceutical industry or relevant experience.
  • Expertise in models of ophthalmic disease, functional vision assessments, and ophthalmic imaging modalities, as well as the application of these techniques to pharmacological studies.
  • Knowledge of functional in vivo endpoints including vision psychophysics, ocular electrophysiology (ERG, VEP) required.
  • Ability to multitask effectively and be adaptable and flexible to meet changing priorities.

About AbbVie

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.



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