LC-MS/MS Method Development Expert
6 days ago
Job Summary:
The Senior Bioanalytical Scientist position at Frontage Laboratories supports method development using LC-MS/MS platform for large molecules (biomarkers, proteins, antibodies, ADCs, Oligonucleotides, etc). This role involves serving as a subject matter expert, reviewing client requests, developing methods, transferring them to the validation team, and troubleshooting challenging methods.
About Frontage Laboratories:
Award-winning Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China. Our core competencies include drug metabolism, pharmacokinetics/pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.
Key Responsibilities:
- Method development using LC-MS/MS platform for large molecule quantitation in biological matrices.
- Method transfer from the method development team to the validation team.
- Project timeline management and data communication to the Principal Investigator.
- Multi-project handling and research for new techniques and procedures.
- Regulatory compliance and training of junior staff.
- Instrumentation setup, utilization, and maintenance.
Requirements and Qualifications:
- Ph.D. or Master's degree in Analytical Chemistry, Biochemistry, Biology, or related scientific discipline.
- 6-10 years of direct experience in bioanalytical method development for large molecules using LC-MS/MS in the biotech, pharma, or CRO industry.
- Demonstrated experience in mass-spectrometry method development for antibodies and ADCs.
- Excellent communication skills and ability to work in a team environment.
- Good knowledge and application of GLP with the ability to train technical personnel.
Compensation Package:
Competitive compensation package including health and dental insurance, a 401(k) plan, disability insurance, and life insurance.
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