Principal Infrastructure Engineer Lead

1 week ago


New York, United States Genesis Therapeutics Full time
Genesis Therapeutics is building a world-class computational team to solve problems in drug discovery through machine learning, biophysical simulation, and computational chemistry. We are looking for a Principal Infrastructure Engineer that is excited to help develop new medicines and play a critical role in building out our AI platform. You Will
  • Lead and manage our infrastructure team to maintain and grow our multi-cloud compute infrastructure that supports our ML model training, computational chemistry research, and ongoing drug discovery efforts
  • Build out our configuration and procedures for monitoring, resource allocation, and deployment automation, as we continue to grow our autoscaling compute clusters to handle larger workloads
  • Work on improvements to our internal job scheduling system to increase our execution throughput, reliability, and compute utilization across heterogeneous pipelines
You Are
  • 5+ years of experience building and maintaining cloud infrastructure at scale, e.g. within AWS or GCP
  • Proficient with Python, Bash, Terraform, and Kubernetes
  • Ideally, experience building and maintaining compute clusters running distributed ML training jobs with 1,000+ GPUs
  • Nice to have: hands-on experience with physical hardware + datacenter management
What We Offer
  • The opportunity to work on high impact infrastructure that is used to accelerate the discovery of new medicines
  • A world-class, tight-knit team of good-hearted people across software, machine learning, computational chemistry, medicinal chemistry, and biology
  • Competitive salary and equity. Medical, dental, and vision insurance, and a 401(k) program
Genesis Therapeutics is unifying AI and biotech to discover novel and breakthrough treatments for patients with severe and devastating conditions. Genesis was founded on groundbreaking molecular ML research and since has established itself as the industry leader in AI for small molecule drug discovery. Our team of accomplished biotech leaders and expert drug hunters joins forces with deep learning researchers and software engineers who are pioneering predictive and generative AI technologies for molecules.
Our team has created the industry's most advanced molecular AI platform called GEMS (Genesis Exploration of Molecular Space), to accelerate and optimize small molecule drug discovery and to enable the discovery of novel first-in-class and best-in-class small molecule drugs for challenging and/or undruggable targets. 
The company has leveraged GEMS to build an internal pipeline with multiple programs against high-value targets, including data-poor and canonically undruggable targets where GEMS is uniquely advantaged. In addition, Genesis has two AI platform collaborations across a range of therapeutic areas: Eli Lilly (signed in 2022, with a $20M upfront payment and a $670M total deal size), and Genentech (signed in 2020). We raised a $200M series B in August 2023, and have raised over $280M in funding from top technology and biotech investors, including Andreessen Horowitz, Rock Springs Capital, T. Rowe Price, Fidelity, Radical Ventures, NVentures (NVIDIA's VC arm), BlackRock, and Menlo Ventures. 
Genesis is headquartered in Burlingame, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer.

  • New York, United States Principal Financial Group Full time

    What You'll Do Join our Principal Infrastructure team as Counsel to provide expert legal guidance in structuring, financing, regulatory, and transactional matters that support Principal Asset Management's growing infrastructure platform. You'll play a vital role in driving sophisticated infrastructure projects and fostering client relationships to ensure our...


  • New York, New York, United States Infrastructure Engineering Full time

    About the Role:">">We are seeking an experienced Civil Project Development Manager to join our team at Infrastructure Engineering Inc. The ideal candidate will have a strong background in civil engineering principles and practices, with expertise in project development, management, and delivery.">Key Responsibilities:">">Lead the development of new projects...


  • New York, New York, United States The Principal Financial Group Full time

    Company OverviewThe Principal Financial Group is a global leader in asset management, with a growing infrastructure platform. As a key member of our Principal Infrastructure team, you will play a vital role in structuring and financing infrastructure projects.


  • New York, New York, United States Infrastructure Engineering Full time

    Job SummaryWe are seeking a highly skilled and experienced Infrastructure Engineering Professional - Senior Civil Specialist to join our team. As a key member of our infrastructure development team, you will be responsible for applying advanced civil engineering principles and practices in a wide range of projects.Key Responsibilities:Engage with clients to...


  • New York, United States Planet Technology USA Full time

    Principal Platform Security EngineerSecurity Platform building / hands-on builder, technical leadership abilities, Python expertiseThis is a Full-Time/Direct Hire position with our client in financial services with offices in NYC and Seattle. 100% Remote. The Principal Platform Security Engineer must be a builder, position requires heavy Python coding,...


  • New York, United States Planet Technology Full time

    Principal Platform Security EngineerSecurity Platform building / hands-on builder, technical leadership abilities, Python expertiseThis is a Full-Time/Direct Hire position with our client in financial services with offices in NYC and Seattle. 100% Remote. The Principal Platform Security Engineer must be a builder, position requires heavy Python coding,...


  • New York, New York, United States Infrastructure Engineering Full time

    Infrastructure Development Executive OpportunityWe are looking for an Infrastructure Development Executive to join our team in New York. As an Infrastructure Development Executive, you will be responsible for leading infrastructure development projects and teams.Your key responsibilities will include:Developing and implementing recovery plans for...


  • New York, United States Capital Group Full time

    "I can succeed as a Distributed Engineering Senior Development Principal at Capital Group." As the Senior Platform Engineer Principal, you will provide strategic engineering leadership and direct, advanced software development for Capital Group's Platform Engineering service. You will be a member of a specialized "Tiger Team", tasked with exploring the...


  • New York, New York, United States Disability Solutions Full time

    Job DescriptionAs a Principal Software Engineering Lead at Disability Solutions, you will be responsible for leading the development of complex software applications using modern technologies such as Spring Boot, Spring Cloud, and PCF. Your expertise will be crucial in driving our company's technology strategy forward.You will work closely with...


  • New York, United States Bluecore Full time

    In the minute it takes you to read this job description, Bluecore has launched over 100,000 individually personalized marketing campaigns for our retail ecommerce customers!Principal Analytics Engineer Summary Principal Analytics Engineer has impact across multiple teams in Bluecore. The role is critical to the technical success of Bluecore as we continue to...


  • New York, New York, United States Big Cloud Full time

    Big Cloud is partnering with a leading company to transform the healthcare industry with AI and blockchain technology.We're seeking a highly skilled Machine Learning Engineer to lead our efforts in developing and deploying innovative ML solutions.As a Principal Machine Learning Engineer, you will be responsible for architecting state-of-the-art ML models and...


  • New York, United States RecruitmentRoom Full time

    About the job Principal Solutions Engineer - Join a team of exceptional leaders (CEO, CPO, CTO) and skilled experts (Software Engineers, Head of Sales) to build the leading blockchain wallet infrastructure for the next financial era. Were seeking a driven and resourceful Principal Solutions Engineer with expertise in technical architecture, client-facing...


  • New York, United States RecruitmentRoom Full time

    About the job Principal Solutions Engineer - Join a team of exceptional leaders (CEO, CPO, CTO) and skilled experts (Software Engineers, Head of Sales) to build the leading blockchain wallet infrastructure for the next financial era. Were seeking a driven and resourceful Principal Solutions Engineer with expertise in technical architecture, client-facing...


  • New York, New York, United States Infrastructure Engineering Full time

    About Infrastructure EngineeringAt Infrastructure Engineering, we're a leading engineering firm committed to delivering quality and excellence in our projects. We're seeking an experienced Civil Engineer I and Civil Engineer II to join our team. As a civil engineer at IEI, you'll be responsible for managing project engineering and document control from the...


  • New York, New York, United States Infrastructure Engineering Full time

    Job Description: As a Civil Engineer I and Civil Engineer II at Infrastructure Engineering, you will perform professional engineering work, including developmental assignments involving the application of standard techniques, procedures, and criteria in carrying out routine engineering tasks under close supervision. Key responsibilities include:Performing...


  • New York, New York, United States Narmi Full time

    Narmi's vision is to revolutionize the way community financial institutions operate, providing them with the tools and expertise needed to compete effectively against larger competitors. Our platform offers a cutting-edge solution for managing customer experiences, driving growth, and enhancing operational efficiency.">About the Opportunity:As a Senior...


  • new york city, United States Planet Technology Full time

    Principal Platform Security EngineerSecurity Platform building / hands-on builder, technical leadership abilities, Python expertiseThis is a Full-Time/Direct Hire position with our client in financial services with offices in NYC and Seattle. 100% Remote. The Principal Platform Security Engineer must be a builder, position requires heavy Python coding,...


  • New York, United States Recruitment Room Full time

    Job DescriptionJob DescriptionJoin a team of exceptional leaders (CEO, CPO, CTO) and skilled experts (Software Engineers, Head of Sales) to build the leading blockchain wallet infrastructure for the next financial era. Were seeking a driven and resourceful Principal Solutions Engineer with expertise in technical architecture, client-facing solutions, APIs,...


  • New York, United States Northrop Grumman Full time

    Requisition ID: RCategory:Information Technology Location:McClellan, California, United States of America Clearance Type:Top Secret Telecommute:No- Teleworking not available for this position Shift:1st Shift (United States of America) Travel Required:Yes, 10% of the Time Relocation Assistance:Relocation assistance may be available Positions Available:1 At...

  • Principal Engineer

    7 days ago


    New York, New York, United States Recruiting From Scratch Full time

    We're a venture-backed start-up looking for a talented Software Engineer to join our team. As a key member of our engineering team, you'll have the opportunity to contribute to the development of our next-generation fashion platform.About the PlatformOur platform uses predictive AI algorithms and generative AI to streamline operations, optimize inventory,...