Vice President, Manufacturing

3 weeks ago


Cambridge, United States FogPharma Full time

FogPharma is pioneering the discovery, development, and commercialization of Helicon TM

peptides, an exciting new drug modality that uniquely combines the cell-permeability of traditional small molecule drugs with the specificity, broad target accessibility and discovery speed of monoclonal antibody drugs. Our patented Helicon peptide technology allows us to modulate the activity of well-known intracellular disease drivers that have thus far evaded small molecule and biologic therapies. FogPharma’s lead program targets β-Catenin, a cancer driver in the WNT pathway. Inhibition of β-Catenin has the potential to benefit more than one-fifth of all cancer patients and is just one of many opportunities for Fog’s lead-discovery platform to change future medicines, therapies and lives. We recently selected a lead development candidate and plan to initiate clinical development early next year. What’s the opportunity? The VP of Manufacturing will be responsible for the overall management of the manufacturing network and planning of the manufacturing strategy to enable cost-effective supply of clinical and future commercial products world-wide. This role reports to the Chief Technical Officer and works closely with Pharmaceutical Development, Clinical, Quality and Finance teams. This is a highly influential role with a significant level of impact across the company. Responsibilities Oversee production operations to ensure that the manufacturing process runs smoothly, efficiently, and on budget. Lead investigations across the manufacturing and distribution network. Assess future clinical and commercial demand of products and planning manufacturing schedules to ensure uninterrupted supply, Selection and negotiation of contracts with suppliers, distributors and CMOs. What you’ll need to be successful: An advanced degree in Chemistry/ Chemical Engineering with a minimum of 15 years of broad-level leadership experience in manufacturing and supply chain management of clinical-stage and commercial pharmaceuticals. Experience in manufacturing of peptides at large scale would be preferable. Experience in negotiating contracts and managing an external manufacturing network of vendors for drug substance, drug product and devices. Demonstrated success in regulatory inspection of manufacturing sites. Knowledge of US and international supply chain architecture including vendor qualification and selection. As an equal opportunity employer, Fog values diversity and welcomes applicants of all backgrounds and experiences. All qualified applicants will receive consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other factors prohibited by law. For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file. As set forth in FogPharma’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law. If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows: A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability. A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service. An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense. An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985. Voluntary Self-Identification of Disability

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For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file. As set forth in FogPharma’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law. Gender

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