Associate Director/Director, Research
3 weeks ago
Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
We are looking for an Associate Director of R&D to support the development of new assays and processes for deployment in our clinical lab related to Tempus’s liquid biopsy portfolio in oncology. This role involves leading a team towards the execution of advanced molecular techniques toward the development of the most advanced sequencing platform in cancer care.
What You’ll Do:
Lead a development and validation team from project inception through launchincluding sample selection, hands-on laboratory validation, establishing workflowand SOPs, and authoring validation plans and summaries
Ensure activities are consistent with project critical path and respondappropriately to changing priorities
Facilitate smooth transfers of developed workflows into clinical lab environments
Evaluate emerging molecular and sequencing technologies and align these to business initiatives and product portfolio needs
Mentor scientific staff on experimental design, continuous learning, and time management
Conduct troubleshooting and quality control initiatives
Assist with the development of automated processes
Provide flexible support for other activities in the clinical Next Generation
Sequencing lab, including emerging technology assessment, LIMS consulting,instrument troubleshooting, etc.
Qualifications:
Master’s degree with 10+ years experience or Ph.D. with 5+ years experience inmolecular techniques
Strong analytical and conceptual capabilities, interpersonal skills, and ability tocommunicate with clarity
Highly organized and systematic, superb attention to detail, and ability to complete tasks with a high degree of accuracy
Track record of assay and/or product development
Hands-on experience with any of the following molecular methods is highly desired:
NGS library preparation methods
Knowledge of liquid biopsy in oncology space
PCR methods such as: PCR, qPCR, RT-PCR, ddPCR
Nucleic acid ligations
Nucleic acid analysis such as: quantitation by absorbance/fluorescence, gel & capillary electrophoresis
Magnetic bead-based DNA/RNA purification and size selection
MLPA
Sanger Sequencing
DNA hybridization arrays
Highly Desirable:
Thrives in a fast-paced environment
Experience with robotics and automated liquid handling systems
Experience in validation of clinical assay validation
Knowledge of LIMS platforms and various computer systems
Experience developing and validating assays according to various US andinternational regulatory body requirements
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