Bench Scientist

1 month ago

Andover, United States Pfizer Full time

The position of an analytical bench scientist specialist is being floated in the Upstream Process Development (UPD) group. The UPD group is responsible for developing robust processes for cell lines producing protein therapeutics. These are proteins that are chosen by research units as the candidate molecules for the treatment of various medical conditions spread across oncology, neuroscience, inflammation, and many others. The processes developed by the UPD group are used in GMP manufacturing facilities to produce the molecules in large quantities for clinical and commercial needs. Almost all the molecules currently produced employ Chinese hamster ovary (CHO) cells as the host cells. One of the vital components of process development is controlling the metabolism of the cells in culture. CHO cells consume large amounts of nutrients including amino acids and other metabolites to produce molecules of interest as well other byproducts. Quantification of amino acids in the culture medium, protein concentration, as well as several other metabolites and byproducts, are key to building robust processes and ensuring product quality. The successful candidate will drive the analytical support to the team by performing analytical tests on culture samples. Responsibilities: Drive analytical support to the UPD team Coordinate with the team to receive and manage samples, perform analytical tests, process the data, and provide it back to the scientists. Perform data analysis using Empower and Microsoft Excel, and compose scientific documents for electronic lab notebooks. Qualifications: Bachelor's or Master's Degree in Biotechnology, Biochemical Engineering, Analytical Chemistry, Chemical Engineering, or other related fields A Minimum of 1+year of related work experience Basic skills in biotechnology and analytical chemistry Hands-on experience or at least a basic knowledge of various analytical, cell culture, and molecular biology techniques including but not limited to amino acid analysis using UPLC, titer assay using HPLC, and metabolite analysis using BioHT. Ability to perform data analysis using Empower and Microsoft Excel Ability to compose scientific documents for electronic lab notebooks Rate/Location: $40-$43/hr This is an onsite role, candidates must be local to Andover, MA Please note contractors are engaged to provide services to Pfizer on a temporary basis in connection with a specific assignment. Contractors are hired and employed through Atrium, our third-party payrolling partner. This job posting is for a temporary role as an employee of Atrium on assignment at Pfizer. The individual selected for this role will be offered the role as an employee of Atrium; compensation, medical benefits, fringe benefits, and other terms and conditions of employment shall be presented by Atrium upon offer. The pay rate range provided is a reasonable estimate of the anticipated compensation range for this job at the time of posting. The actual pay rate will be based on a number of factors, including skills, competencies, experience, location and/or being pursued, and other job-related factors permitted by law. In addition, this role will be eligible for overtime pay, in accordance with federal and state requirements. #J-18808-Ljbffr

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