Senior Scientist

5 days ago

Silver Spring, Maryland, United States Culmen International LLC Full time
About the Role

Culmen International is hiring

Senior Scientists

to provide support for the

Walter Reed Army Institute of Research Experimental

Therapeutics

Program (WRAIR ET)

and

will be onsite in Silver Spring, Maryland.

Experimental Therapeutics (ET) is a drug discovery and development enterprise created to protect military personnel from death, disease, and injury and meet Army and DOD mission requirements. While its historical focus has been radioprotection and parasitic disease, ET applies its core competencies of medicinal, synthetic, and analytical chemistry as well as clinical pharmacology to all therapeutic areas within the Medical Research and Development Command's portfolio. ET has a 75-year legacy of excellence in small molecule drug development, with over 65 Investigational New Drug (IND) applications submitted to the U.S. Food and Drug Administrations (FDA).

What You'll Do in Your New Role

Lead in vitro testing for the Combating Antibiotic-Resistant Bacteria (CARB) group
Lead, guide, and coordinate efforts within a multidisciplinary research group to execute in
vitro and in vivo studies aimed at developing antibacterial small molecule drugs to prevent
and/or treat complex wound infections in a prolonged care environment
Collaborate with in vivo team partners to assess potential efficacy of antibacterial small
molecule drugs using the neutropenic mouse thigh infection model
Design and implement in vitro HTS assays (MIC, synergy) involving robotic liquid handlers to
screen compound and large (~100 strains) bacterial libraries
Collect and analyze large datasets using analytical software to make detailed observations and
meaningful interpretations of the resultsCommunicate regularly with government and industry collaborators through written reports
and oral presentations to provide project updates and conclusions of research findings
Prepare and finalize scientific documentation such as grants, SOPs, and tech transfer forms

Required Qualifications

Master's Degree biological sciences or equivalent.
6+ years of relevant experience
Demonstrated experience in leading projects (personnel and research efforts), submitting proposals for research efforts, and performing data analysis and reporting.
Demonstrated subject matter expertise in design, development, validation, and performance of in vitro assays for antimicrobials, antivirals, and/or antibacterial drug development.
Demonstrated expertise with liquid-handling robotics, tissue culture, aseptic technique, and high content imaging.
Demonstrated expertise handling BSL 1 and 2 infectious agents, toxic chemicals, and blood-borne pathogens.

Desired Qualifications

Ph.D.

About the Company

Established in 2004, Culmen International is committed to enhancing international security, strengthening homeland defense, optimizing government operations and providing humanitarian assistance around the world. We provide technical and management expertise, develop innovative technology solutions, and deliver youth care services, logistics, training and language services worldwide. With experience in over 140 countries, Culmen supports our clients to accomplish critical missions in challenging environments.

Exceptional Medical/Dental/Vision coverage with 100% of the premiums paid by the company for all employees and their eligible dependents
401k - Vested immediately and 4% match
Life insurance and disability paid by the company
AFLAC Available
Tuition Assistance
12 Paid Holidays

At Culmen International we are committed to creating, promoting, and sustaining a culture of diversity, equity, and inclusion. Our commitment to these values is unwavering across all our work around the world. We include and celebrate employees of diverse races, genders, religions, sexual orientations, ethnicities, nationalities, socioeconomic statuses, languages, (dis)abilities, ages, and religious commitments. These differences drive innovative solutions to meet the needs of our employees and clients. Culmen is an equal opportunity employer.

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