Scientist I

4 weeks ago

Rockville, United States SciNeuro Pharmaceuticals Full time

**The Company**

SciNeuro Pharmaceuticals is a clinical-stage biotechnology company focused on developing disease-modifying therapies for neurodegenerative diseases. Since its founding in 2020, SciNeuro has built a portfolio of pipeline programs staged from discovery to early clinical development by addressing three key disease-driving mechanisms of neurodegeneration - neurovascular inflammation, proteinopathy, and immune response. These interactive mechanisms allow for multiple and exciting treatment options for the various indications the company is developing therapies for including Alzheimer’s disease, Parkinson’s disease, and other devastating CNS diseases. Since its founding in 2020, SciNeuro has already established itself as a recognized player in neurodegeneration. SciNeuro has formed collaborations with GSK, Eli Lilly, and numerous other innovative partners who provide the company with access to unique and differentiated technologies. With its $100M Series A financing round, SciNeuro is backed by blue-chip investors led by ARCH Venture Partners and Lilly Asia Ventures.

**The Position**

**What you will love about this Opportunity**
- A fast-growing company with great career advancement potential.
- Great team and great science. You will be working with world-renowned neuroscientists and senior leaders from large pharma/top CRO/CDMO and top academic medical centers with solid scientific, industrial, and managerial experience.
- A company operating mainly in the US with a global footprint which could be a great learning experience to develop skills in a multi-national environment.
- A collaborative organization with cross-team communications internally covering different business units, and locations and externally with vendors, partners, etc.

**Location**:Rockville, Maryland, USA

**Key responsibilities**:

- Perform cutting-edge research in neurological disorders to support SciNeuro’s drug discovery programs.
- Gene cloning, plasmid preparation, antibody expression and purification, antibody QC using PAGE and HPLC
- Perform antibody discovery experiments using single B cell sorting/cloning, phage and/or yeast library construction and screening.
- Antibody characterization using a variety of methods such as Western Blotting, ELISA, Flow Cytometry, and binding affinity measurement using Octet/Biacore.
- Prepare and submit samples, analyze, and report the data, and maintain safe and efficient lab operations.
- Keep records of all experiments in a laboratory notebook to ensure data integrity and reproducibility Assist in design and execution of a variety of lab experiments per program needs.

**Core Qualifications and Experience**
- Ph.D. degree in cell and molecular biology, biochemistry, immunology, neurobiology, or related field, with relevant antibody discovery experience for over two years.
- Familiar with antibody discovery platforms such as single B cell sorting/cloning, phage and/or yeast library construction and screening.
- Experience with antibody affinity measurement using Octet, experience with epitope binning.
- Experience with techniques for antibody characterization such as ELISA, flow cytometry, and HPLC is preferred.
- Experience in antibody PCR, gene cloning, expression and purification is preferred.
- Experience in a variety of cellular, molecular biology and/or protein chemistry-related methods.
- A team player who also has resilience and will be comfortable with complexity and collaborative work.
- Good communication skills (oral and written).

Pay: $90,000.00 - $110,000.00 per year

**Benefits**:

- 401(k)
- 401(k) matching
- Dental insurance
- Health insurance
- Life insurance
- Paid time off
- Parental leave
- Relocation assistance
- Retirement plan
- Vision insurance

Medical specialties:

- Neurology

Schedule:

- Day shift
- Monday to Friday
- Weekends as needed

Work Location: In person

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