Postdoctoral Fellow

2 weeks ago

Austin, United States University of Texas at Austin Full time

Job Posting Title:
Postdoctoral Fellow
- Hiring Department:
Molecular Biosciences
- Position Open To:
All Applicants
- Weekly Scheduled Hours:
40
- FLSA Status:
Exempt
- Earliest Start Date:
Immediately
- Position Duration:
Expected to Continue Until May 05, 2025
- **Location**:
AUSTIN, TX
- Job Details:
General Notes

PhD must have been received within the past 3 years. This is a temporary training position that can be renewed annually, for a maximum of five years, based upon performance review, progress towards research goals, and continuation of funding.

Purpose

The Ehrlich lab is seeking a motivated postdoctoral fellow to study mechanisms by which myeloid cells promote progression of T-cell acute lymphoblastic leukemia (T-ALL). Our previous research revealed that heterogeneous myeloid cells become altered in leukemic microenvironments to support T-ALL progression. We are currently pursuing research to identify the underlying cellular and molecular mechanisms of myeloid-mediated T-ALL support, with the goal of designing novel therapeutic strategies. The postdoctoral fellow will design and implement in vitro and in vivo assays using mouse models of T-ALL and primary patient samples to identify myeloid cell types and associated signals that support distinct molecular T-ALL subtypes, and they will assist in analysis of single-cell transcriptional profiling data to develop novel testable hypotheses.

The Postdoctoral fellow will be encouraged to develop as an independent scientist within the collaborative and supportive environment of the Ehrlich lab. They will also have opportunities to gain mentorship experience working with our talented undergraduate and graduate trainees at UT Austin.

**Responsibilities**:
- Perform and analyze in vitro and in vivo experiments to determine how myeloid cells in the leukemic microenvironment of different organs promote progression of T-ALL.- Manage mice needed for experiments and freeze new primary T-ALL stocks and donor PBMCs.- Mentor and collaborate with undergraduate and graduate students carrying out T-ALL research.- Prepare presentations for lab meetings, journal clubs, and other external conferences/meetings; coordinate collaborative analysis of transcriptional profiling data with bioinformatics collaborators, prepare figures and write manuscripts to disseminate research to the scientific community.

Required Qualifications

PhD in immunology, cancer biology, or a related field and experience working with mouse models. The ideal applicant will have a strong background in immunology and/or cancer biology, experiments using genetically modified mouse models, flow cytometry and mammalian cell culture.

Preferred Qualifications

Experience with flow cytometry, histology and immunofluorescence imaging, transcriptional profiling analyses (including scRNAseq), mammalian cell culture. Experience with gene expression analysis and immunofluorescence imaging is desirable.

Salary Range

$61,008 + depending on qualifications

Working Conditions- Uniforms and/or personal protection equipment (furnished).- May work around chemical fumes.- May work around standard office conditions.- May work around biohazards.- May work around chemicals.

Required Materials- Resume/CV- 3 work references with their contact information; at least one reference should be from a supervisor- Letter of interest
- Employment Eligibility:
Please make sure you meet all the required qualifications and you can perform all of the essential functions with or without a reasonable accommodation.
- Retirement Plan Eligibility:

- Background Checks:
A criminal history background check will be required for finalist(s) under consideration for this position.
- Equal Opportunity Employer:
The University of Texas at Austin, as an

equal opportunity/affirmative action employer

, complies with all applicable federal and state laws regarding nondiscrimination and affirmative action. The University is committed to a policy of equal opportunity for all persons and does not discriminate on the basis of race, color, national origin, age, marital status, sex, sexual orientation, gender identity, gender expression, disability, religion, or veteran status in employment, educational programs and activities, and admissions.
- Pay Transparency:
The University of Texas at Austin will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted

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