Scientist Ii

**About the Department**

Our Boston Research & Development hub, anchored in the greater Boston area, brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown and Cambridge reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. Our greater Boston R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients.

The team is comprised of collaborative, diverse and passionate people who have a true sense of pride in their work and are committed to helping others grow and develop their careers. You’ll also have a platform to engage with key stakeholders on a global scale throughout the entire pipeline process. And while changing the future of diabetes, obesity and MASH is no easy task, we also recognize the importance of an enjoyable workplace, which is why we’ve cultivated a culture of fun, ingenuity and innovation. And our competitive compensation package and support of a healthy work-life balance all add to a best-in-class employee experience. We are changing lives for a living. Are you ready to make a difference?

**The Position**

**Relationships**

This is a full-time position located in Boston area. This position will report to the head of In vivo Pharmacology at Novo Nordisk in Boston.

Internal relationships include working closely with technical staff & other members of the scientific leadership team; regular collaborations with members of other research departments in Boston; & frequent interaction with project managers & other colleagues in Denmark, Oxford and Beijing. Individual may be responsible for indirect reports or contingent workers.

Individual will interact with external research collaborators, both academia
- & industry-based.

**Essential Functions**
- Major contributor to research projects through hands-on in vivo work within obesity and cardiometabolic disease areas, in vivo pharmacology, involving highly complex activities, receiving mínimal guidance
- Extensive pharmaceutical industry experience with executing rodent in vivo workflows and experimental designs with ethical considerations
- Technical expertise in in vivo techniques including animal dosing and handling, ICV, in-life measurements, sample collections and necropsies is required
- Experience with mini-pump implantations and telemetry surgeries is highly desired
- Lead research projects (target, biology, or technology-related) involving coordination of multiple experimental activities and groups
- Expands the capabilities of early target discovery through the generation of new target ideas, evaluation of biology or methods, and implementation of technologies that add value
- Responsible for ensuring realistic project timelines and deliverables and works closely with local or global project managers
- Analyzes and interprets complex data with high degree of sophistication, drives conclusions, and next steps
- Experience with in silico analyses and large datasets is highly desired
- Author internal reports, protocols, and external publications
- Effectively communicates and collaborates across global sites and guides project strategy by providing expert input to cross-functional project teams
- Represents the organization at scientific conferences and global meetings by authorship and publication of scientific papers and patents
- Maintains a strong understanding of theoretical knowledge and a connection to the external scientific community through continuous evaluation of relevant literature
- Leads cross-functional experimental teams to achieve project goals, mentor junior staff, and provide training
- Influences the research pipeline by recommending, presenting, and championing new targets or methodologies
- Works with Department Heads and Scientists to ensure better practice sharing and implementation within the research environment

**Qualifications**
- 15+ years’ relevant experience required, or a master’s degree with 10+ years’ relevant experience, or a Doctoral degree in with 4+ years’ post-doctoral and/or industry relevant experience can be considered
- Extensive pharmaceutical industry experience with In vivo rodent dosing via several routes of administration, intracranial injections, perfusions, necropsies, blood collection, PK/PD studies and model characterization is required
- Experience working with rat models systems, samples collections and necropsies is highly desired
- Surgical skills and experience with in vivo imaging is highly desired
- Demonstrates excellent verbal and written communication skills
- Demonstrates outstand