Director Myeloma Disease Lead Translational Medicine

3 weeks ago

Redwood City, United States Bristol-Myers Squibb Full time

**Working with Us**
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb is an integrated global biopharmaceutical company engaged primarily in the discovery, development, and commercialization of novel therapies in the areas of hematology/oncology, cardiovascular and inflammatory diseases through innovative small molecule, biologicals and cell therapy approaches.

BMS R&D is at a critical and exciting phase of development. As it expands and integrates its portfolio with recent and exciting new acquisitions, there is an opportunity for a science-driven, dynamic and ambitious individual to aid in leading our reverse translational efforts in multiple myeloma within our Hematology Translational Medicine Department at our site in Summit, New Jersey.

Translational Medicine is part of the Global Research and Early Development organization in BMS and leads mid
- to late-stage clinical, pharmacological, and translational research and development activities for the BMS hematology pipeline. The Translational Medicine team supports the late-stage portfolio for regulatory, translational development and life cycle management. Translational Medicine Hematology at BMS has a long-standing history of scientific rigor as evidenced by our peer-reviewed publications, delivery of drug approvals including Revlimid, Pomalyst, Idhifa, Inrebic, Onureg and Reblozyl, strong academic collaborations and talent development. Our areas of focus include but are not limited to multiple myeloma, acute myeloid leukemia/MDS, lymphoma and erythroid disorders. This group integrates scientific learnings from the lab and clinic as well as business insights of multiple functions and leads the development of translational strategies at the franchise level.

Technical Skills
- In-depth understanding of multiple myeloma disease, the evolving diagnostic, treatment, clinical development and reimbursement landscape and competitive scenarios
- Strong relationships with multiple myeloma physician-scientist KOLs at key institutions in USA and Europe
- Strong understanding of clinical, translational, and mechanistic data of current myeloma therapies in both NDMM and RRMM, including, IMiDs, CELMoDs and immune redirecting therapies.
- Strong background in strategy development
- Background in tumor genomics and/or single cell analysis
- Understanding of late-stage drug and translational development process
- Proven ability to work with global disease teams to develop strategies to support life cycle management efforts tailored to regional markets (i.e, US, EU, CAN)
- Strong verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications/reviews, disease strategies, mechanism slides, regulatory submissions, strategic communications, literature/market/pt segment analyses
- Proven scientific/project leadership expertise (working in teams, managing people/projects)
- Ability to synthesize complex scientific and business problems into strategy and tactics
- Basic understanding of IP, contracting terms and provisions

**Responsibilities**

Strategy Role
- Lead the long-term disease strategy goals and objectives in multiple myeloma by working with MM asset leads and project managers and taking ownership of myeloma disease goals
- Lead multiple myeloma above asset genomics/immune internal and external projects (eg, external collaborations, identification of high-risk disease and patient segments) including establishing new collaborations and strategic partnerships with key KOLs and Institutions
- Represent TM in cross-functional Strategy and Disease-oriented Global Project Teams (such as MRD)
- Support efforts to implement molecular profiling and routine MRD assessment efforts in multiple myeloma internally and externally
- Interface with Commercial including early commercialization group, Global Drug Development, and Medical Affairs to provide scientific support for cross-functional TM goals
- Lead the communication strategy for the multiple myeloma disease team including regulatory submissions, lead and manage the development of key publications internally and with collaborators

Development Role
- Participates in development of pipeline differentiation strategy (such as CELMoDs, sequencing of BCMA therapies)
- Leads the development of myeloma above-asset translational annual goals and objectives and is accountable for their execution in association wit

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