Scientist, In Vivo Process Development Downstream

We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet.
Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows.

Job Description
The Scientist, In Vivo Process Development Downstream role designs and executes downstream/purification experiments to support development of manufacturing processes for Lentivirus.
This role applies advanced chemistry, biochemistry, and/or engineering principles to deliver robust, scalable processes, supports manufacturing activities and process optimization at scale, and operates with broad autonomy and limited oversight. The Scientist is accountable for end-to-end process performance, scientific soundness, and technical leadership while training and mentoring colleagues.

Key Responsibilities
Design and optimize scalable, safe, and cost-effective downstream process for Lentivirus manufacturing.
Develops technical solutions to complex problems requiring ingenuity and creativity, applying advanced scientific/engineering principles to ensure scientific soundness and performance.
Supports manufacturing activities and process optimization at scale, contributing technical expertise to improve process performance and scalability.
Manages day-to-day laboratory operations, including planning work, maintaining efficient lab execution, and ensuring effective documentation practices.
Keep accurate, detailed laboratory records and comply to all required training and safety guidelines.
Apply statistical methodologies and basic modelling approaches to design experiments, perform data analysis, and interpret data.
Trains, guides, and mentors colleagues by sharing technical skills, coaching on process execution, and troubleshooting, and strengthening team capability.
Communicates technical outcomes in technical reports and presentationsInterface with multidisciplinary groups to solve complex issues and promote collaboration.
Works independently with broad autonomy and limited oversight; determines approaches for moderately complex assignments under minimal direction.
Education and ExperienceB.
S., M.
S, PhD/PharmD in science or engineeringBS with 6+ years post-graduate relevant experience in bioprocess/biotechnology, orMS with 4+ years post-graduate relevant experience in bioprocess/biotechnology, orPhD/PharmDRequired QualificationsMust have strong scientific understanding and demonstrated hands-on proficiency of downstream unit operations for large biomolecules (e.g. protein, virus) such as chromatography and filtration.
Sound understanding of bioprocess scale-up principles for large biomoleculesWorking knowledge of cGMP principlesProficiency in Microsoft Word, Excel, Power Point, and data analysis software such as JMP, GraphPadProven ability to collaborate in a dynamic team environmentExcellent interpersonal, verbal, and written communication skillsStrong organization and problem-solving skills with excellent attention to detailsPreferred Experience and SkillsPrior experience with process development of viral vectorsPrior experience with the use of Design of Experiments (DOE) to support process development experiments.
Prior experience with fermentation/cell culture and analysis of large biomoleculesHands-on experience with large scale bioprocessing in either non-GMP or GMP settingDemonstrated mentorship and team leadershipThe salary range for this position is: $133,195.00
- $172,370.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.
For additional benefits information, visit:
* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.
Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell