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Director of Bio Machine Learning

1 month ago


San Diego, United States University of California San Diego Full time

Director of Bio Machine Learning UC San Diego values and welcomes people from all backgrounds. If you are interested in being part of our team, possess the needed licensure and certifications, and feel that you have most of the qualifications and/or transferable skills for a job opening, we strongly encourage you to apply. Apply by 09/12/2025 for consideration with preference for rehire (layoff applicants should contact their Employment Advisor). Eligible Special Selection clients should apply by 09/23/2025 and contact their Disability Counselor for assistance. The qualifications of this posting have been slightly modified as of 9/09/2025 This position has recently been accreted by UAW RP union and will be a part of that union moving forward. DESCRIPTION The Ideker Laboratory at UCSD is recruiting a Director of Bio Machine Learning (BioML) to lead R&D efforts for the ADAPT project, a new precision cancer therapy initiative funded by ARPA‑H. The overall goal of the ADAPT project is to use advanced AI/ML technologies to deliver the right therapy to the right patients at the right time. ADAPT will revolutionize cancer treatment by using predictive biomarkers and interpretable AI/ML to create dynamic cancer treatment strategies and personalized therapies for patients with metastatic cancers. The Director of Bio Machine Learning will oversee AI/ML research projects and objectives toward the successful completion of the ARPA‑H ADAPT program goals, including providing direction and support to the team. This role will require expertise in computer science, bioinformatics, AI/deep learning, systems biology, modern cancer biology, and project leadership. In particular, this position will: * Lead the design and implementation of deep learning approaches for drug recommendation in cancer. * Lead interdisciplinary teams by collaborating with biologists, oncologists, statisticians, and other computational/ML scientists to translate computational findings into therapeutic strategies. * Design, debug, and optimize algorithms and computational techniques to analyze and fuse complex, multimodal datasets, including genomic, transcriptomic and proteomic data from various sources for biomarker discovery and therapy recommendation. * Create and validate computational tools to track tumor changes and adapt therapy plans in real‑time using insights from clinical data. * Create and oversee a central benchmarking platform for standardizing AI/ML models. * Contribute to the creation and maintenance of a central cancer treatment and analysis platform, ensuring accurate and timely data availability for clinicians and researchers. * Provide mentorship and guidance to junior researchers, including PhD students and postdocs, fostering expertise in bioML and its applications in oncology. * Prepare detailed reports, publications, and presentations showcasing progress on ADAPT program goals, and represent the lab at national and international conferences. * Collaborate closely with the Ideker Lab's Program Director to identify and pursue new funding opportunities, align lab objectives with emerging trends in precision medicine, and contribute to grant proposals to support long‑term research initiatives. * In addition to the main ADAPT initiative, we expect that this position will work on and potentially lead other projects within the Ideker Lab research portfolio as needed. About the Ideker Laboratory: The Ideker Laboratory is in the Division of Human Genetics and Precision Medicine at UC San Diego School of Medicine. We are a vibrant research team of 30‑40 staff, postdocs, graduate students, and undergraduate students known for its dynamic and collaborative environment. We perform bioinformatics research coupled with wet‑lab investigations, working in the areas of network biology, data‑driven hierarchical modeling, and machine learning applied to biomedicine. We also support multiple open‑source software projects, some with 100K+ users. Additional Information: Applies advanced computational, computer science, data science, and CI software research and development principles, with relevant domain science knowledge where applicable, to perform highly complex research, technology and software development which involve in-depth evaluation of variable factors impacting medium to large projects of broad scope and complexities. Designs, develops, and optimizes components / tools for major HPC / data science / CI projects. Resolves complex research and technology development and integration issues. Gives technical presentations to associated research and technology groups and management. Evaluates new hardware and software technologies for advancing complex HPC, data science, CI projects. May represent the organization as part of a team at national and international meetings, conferences and committees. Assists in the design, implementation and recommends new hardware and software technologies for advancing complex HPC, data science, CI projects. May lead a team of research and technical staff. MINIMUM QUALIFICATIONS * Nine years of related experience, education/training OR Bachelor's degree in a related area and/or equivalent experience/training. Bachelor's, Master's or PhD in Computer Science, Mathematics, Statistics, or related discipline strongly preferred. * Advanced knowledge of HPC / data science / CI. * Highly advanced skills, and demonstrated experience associated with one or more of the following: HPC hardware and software power and performance analysis and research, design, modification, implementation and deployment of HPC or data science or CI applications and tools of large‑scale scope. * Demonstrated ability to regularly, effectively communicate with unit‑level management. * Demonstrated ability to communicate technical information to technical and non‑technical personnel at various levels in the organization and to external research and education audiences. * In‑depth skills and experience in independently resolving complex computing / data / CI problems using introductory and/or intermediate principles. * Self‑motivated and works independently and as part of a team. * Advanced experience working in a complex computing / data / CI environment encompassing all or some of the following: HPC, data science infrastructure and tools / software, and diverse domain science application base. * In‑depth ability to successfully work and/or lead multiple concurrent projects. Demonstrated research and technology project leadership and management skills. * In‑depth experience assessing a broad spectrum of technical and research needs and demands and establishing priorities, delegating and/or leading development of solutions to meet such needs. * Demonstrated advanced experience in one or more of the following: optimizing, benchmarking, HPC performance and power modeling, analyzing hardware, software, and applications for HPC / data / CI. * Advanced knowledge of deep learning model architectures and modern AI/ML technologies. PREFERRED QUALIFICATIONS * Knowledge of modern cancer biology, omics, and systems biology. * Demonstrated ability to initiate research proposals and acquire funding. SPECIAL CONDITIONS * Employment is subject to a criminal background check. PAY TRANSPARENCY ACT Annual Full Pay Range: $119,400 - $230,800 (prorated if the appointment percentage is less than 100%) Hourly Equivalent: $57.18 - $110.54 Factors in determining the appropriate compensation for a role include experience, skills, knowledge, abilities, education, licensure and certifications, and other business and organizational needs. The Hiring Pay Scale referenced in the job posting is the budgeted salary or hourly range that the University reasonably expects to pay for this position. The Annual Full Pay Range may be broader than what the University anticipates to pay for this position, based on internal equity, budget, and collective bargaining agreements (when applicable). If employed by the University of California, you will be required to comply with our Policy on Vaccination Programs, which may be amended or revised from time to time. Federal, state, or local public health directives may impose additional requirements. If applicable, life‑support certifications (BLS, NRP, ACLS, etc.) must include hands‑on practice and in‑person skills assessment; online‑only certification is not acceptable. Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached. To foster the best possible working and learning environment, UC San Diego strives to cultivate a rich and diverse environment, inclusive and supportive of all students, faculty, staff and visitors. For more information, visit UC San Diego Principles of Community. The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law. For the University of California's Anti‑Discrimination Policy, please visit: https://policy.ucop.edu/doc/1001004/Anti-Discrimination. UC San Diego is a smoke and tobacco free environment. Please visit smokefree.ucsd.edu for more information. UC San Diego Health maintains a marijuana and drug free environment. Employees may be subject to drug screening. #J-18808-Ljbffr