Scientist I
4 weeks ago
Position We are seeking a talented and highly motivated scientist with a strong background and hands-on experience in bioconjugation to join our Discovery Chemistry team. In this laboratory-based position, you will play a pivotal role in the development of cutting-edge Degrader-Antibody Conjugates (DACs) across various therapeutic areas. The successful candidate will have the opportunity to directly contribute to the following key platform operations : Develop, optimize and implement high-throughput bioconjugation processes through the application of established and state-of-the-art technologies Execute high-throughput preparation of novel antibody drug conjugates at milligram scale Contribute to the design and synthesis of linkers and linker-payloads to enhance conjugate properties Prepare, purify and characterize bioconjugates to support in-vitro and in-vivo studies Contribute to the collaborative efforts focused on the development and optimization of bioanalytical protocols to evaluate critical quality attributes of DACs Engage in cross-functional discussions and contribute to scientific strategies and team goals focused on advancing Nurix’s Degrader-Antibody Conjugate (DAC) discovery programs Prepare reports and present data at internal group meetings Education and Experience Ph.D. in Organic Chemistry, Chemical Biology, Biochemistry, or related field with up to 4 years relevant experience OR MS with 6+ years relevant experience, OR BS or equivalent with 10+ years relevant experience Experience with high-throughput automated workflows to produce bioconjugates Hands-on laboratory experience in carrying out diverse conjugation chemistry protocols, linker-payload synthesis and related processes to produce high-quality drug conjugates Familiar with the general workflow operations, instrumentation and practices used for the generation of antibody-drug conjugates Experience characterizing and purifying bioconjugates using common analytical tools Experience working in the drug discovery chemistry field – linker design, synthesis, and SAR based property optimization of small molecules Established track record of conference presentations and peer-reviewed publications in the areas of antibody drug conjugation and organic synthesis Strong written and verbal communication skills Added Quantifications Postdoctoral or industrial work experience in the bioconjugation field Experience working in Antibody-Drug Conjugate (ADC)- or Degrader-Antibody Conjugate (DAC)- based drug discovery programs Experience working with bioanalytical tools such as hydrophobic interaction chromatography (HIC), preparative-scale size exclusion chromatography (SEC), liquid chromatography-mass spectrometry (LC-MS), ion-exchange (IEX), and reversed phase (RP)-HPLC, Nuclear Magnetic Resonance (NMR) Spectroscopy Experience carrying out assays to evaluate in-vitro stability of ADC and payloads such as Cathepsin B, esterase activity and free drug analysis Fit with Nurix Culture and Values Strong team orientation and highly collaborative Solutions and results-oriented focus Hands-on approach; resourceful and open to diverse points of view Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job with Nurix or in the course of your employment with Nurix. By applying for a position at Nurix, you agree to our collection and use of personal information as described in our Privacy Policy. #J-18808-Ljbffr
-
Translational Research Scientist
4 weeks ago
San Francisco, United States Innova Full timeA client of Innova Solutions is immediately hiring for a Translational Research Scientist, I (Assistant )Role: Translational Research Scientist I (Assistant )Position type: full-time ContractDuration: 12+ months
-
Associate Scientist I, Translational Medicine.
4 weeks ago
San Francisco, United States Innova Full timeA client of Innova Solutions is immediately hiring for an Associate Scientist I, Translational Medicine. Position type: Full-time Contract, potential contract to hire Duration: 12+ months Location: South SFO 94080 USA (Onsite Role) Position: Associate Scientist I, Transla
-
Scientist I Formulations Job
23 hours ago
San Francisco, California, United States R&D Partners Full timeJob OverviewWe are seeking an experienced Associate Scientist I, Formulations to join our client's team in San Carlos, CA. This is a critical role that requires exceptional scientific knowledge and laboratory skills to support formulation development.Main Responsibilities:Development and implementation of formulation strategies to support analytical and...
-
Scientist I
4 weeks ago
San Francisco, United States Pace Analytical Services Full timeAbout UsPace Analytical Services Pace makes the world a safer, healthier place. Committed to advancing the science of businesses, industries, consulting firms, government agencies, and others, Pace offers local-level service backed by a national laboratory network. Through in-lab and emergency onsite services, Pace ensures our air, water, soil, and more are...
-
Senior Scientist I
1 day ago
San Francisco, United States Jobleads-US Full timeSelect how often (in days) to receive an alert: Create AlertSenior Scientist I (Downstream Process Development)Location: CA-San Francisco, USContract Type: Regular Full-TimeArea: Research & DevelopmentWould you like to join an international team working to improve the future of healthcare? Grifols is a global healthcare company that since 1909 has been...
-
Scientist I, DMPK
4 days ago
South San Francisco, United States Maze Therapeutics Full timeJob DescriptionJob DescriptionThe Position:The Drug Metabolism and Pharmacokinetics (DMPK) team at Maze Therapeutics is seeking a qualified and highly motivated Scientist I to join us in advancing our therapeutic programs. In this lab-based role, you'll apply your expertise in LC-MS/MS (QQQ) and/or LC-HRMS (Orbitrap) to measure concentrations of small...
-
Scientist I, DMPK
16 hours ago
South San Francisco, United States Maze Therapeutics Full timeJob DescriptionJob DescriptionThe Position:The Drug Metabolism and Pharmacokinetics (DMPK) team at Maze Therapeutics is seeking a qualified and highly motivated Scientist I to join us in advancing our therapeutic programs. In this lab-based role, you'll apply your expertise in LC-MS/MS (QQQ) and/or LC-HRMS (Orbitrap) to measure concentrations of small...
-
Scientist I
5 days ago
San Francisco, United States PinkDx, Inc. Full timePosition Summary:PinkDx is seeking a motivated Scientist I, Product Development to join us in our journey to improve women’s health. This position will be part of a team developing NGS-based molecular diagnostic assays for use in clinical labs in collaboration with cross-functional groups. The successful candidate will have solid knowledge in molecular...
-
Associate Scientist I, Formulations
7 days ago
San Francisco, United States R&D Partners Full timeJob DescriptionJob DescriptionR&D Partners is seeking to hire an Associate Scientist I, Formulations in San Carlos, CA.A quickly-growing, clinical-stage vaccine company is looking for an energetic and talented individual to play a key supporting role in the Formulation Development function. They would support manufacture of drug products to support...
-
Scientist I
4 weeks ago
San Francisco, United States Cepheid Full time €68,000 - €93,000At Cepheid, we are passionate about improving health care through fast, accurate diagnostic testing. Our mission drives us, every moment of every day, as we develop scalable, groundbreaking solutions to solve the world's most complex health challenges. Our associates are involved in every stage of molecular diagnostics, from ideation to development and...
-
EHS Scientist I
3 weeks ago
San Francisco, United States Alta E&I Full timeJob Description Job Description General Summary: Alta Environmental is a leading environmental company dedicated to sustainable practices and the preservation of the environment. We specialize in providing innovative solutions to manage hazardous materials and promote eco-friendly practices among business and communities. We are committed to creating a...
-
San Francisco, United States Jobleads-US Full timeAssociate Scientist I, Translational Medicine - Healthcare & ResearchJob ID: 991360South San Francisco, CaliforniaJob Type: ContractAdded: 12/30/24Job DescriptionA client of Innova Solutions is immediately hiring for an Associate Scientist I, Translational Medicine.Position type: Full-time Contract, potential contract to hireDuration: 12+ monthsLocation:...
-
Medical Laboratory Scientist I
5 days ago
San Francisco, United States Baylor Scott and White Medical Center - Frisco Full timeMedical Laboratory Scientist I / FT Under the general direction of the Laboratory Director, provides superior quality laboratory testing support. Complies with the department policies, processes, and procedures to provide accurate results, quality products, and services; assures valid results in the pre-analytical, analytical, and post-analytical phases of...
-
Scientist 2/ Scientist 3
2 weeks ago
San Francisco, United States Genentech Full timeThe PositionScientist 2/ Scientist 3, Complex in Vitro SystemsWe advance science so that we all have more time with the people we love.The Complex in Vitro Systems (CiS) Lab within the department of Translational Safety in Genentech Research and Early Development (gRED) is seeking a driven and inquisitive Scientist 2/3 to develop, characterize, and qualify...
-
Energy Supply Data Scientist I
3 weeks ago
San Francisco, United States PacifiCorp Full time €78,500 - €127,400Energy Supply Data Scientist I & II, Portland OR () Date: Jan 31, 2025 Location: PORTLAND, OR, US, 97232 Company: PacifiCorp JOIN OUR TEAM! PacifiCorp is seeking customer-centric candidates to grow and sustain our commitment to a culture of customer service excellence, environmental sustainability and diversity, equity and inclusion. General Purpose The...
-
Scientist I/II, Antibody Discovery
4 weeks ago
San Francisco, United States Abalone Bio Full timeScientist I/II, Antibody Discovery (AB2025-101)https://www.abalonebio.com/careers/ab2025-101About Abalone BioAbalone Bio is a San Francisco Bay Area, preclinical-stage biotechnology company developing antibody drugs for G protein-coupled receptors (GPCRs), ion channels and other membrane protein targets. We are developing our own therapeutics as well as...
-
Medical Laboratory Scientist I
2 weeks ago
San Francisco, United States Baylor Scott and White Medical Center - Frisco Full timeMedical Laboratory Scientist I / FT Under the general direction of the Laboratory Director, provides superior quality laboratory testing support. Complies with the department policies, processes, and procedures to provide accurate results, quality products, and services; assures valid results in the pre-analytical, analytical, and post-analytical phases of...
-
Medical Laboratory Scientist I
5 days ago
San Francisco, United States Jobleads-US Full timeMedical Laboratory Scientist I / PRN Under the general direction of the Laboratory Director, provides superior quality laboratory testing support. Complies with the department policies, processes, and procedures to provide accurate results, quality products, and services; assures valid results in the pre-analytical, analytical, and post-analytical phases of...
-
Sr. Clinical Scientist
3 days ago
San Francisco, United States Star Therapeutics Full timeOur mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life. For more information, see our website at altoslabs.com. Our Value Diversity at Altos We believe that diverse perspectives are foundational to scientific innovation and inquiry. At Altos, exceptional...
-
Research Scientist I-II
4 weeks ago
San Diego, United States Sapient Bioanalytics, LLC Full timeSapient is a fast-growing early-stage biotech company headquartered in San Diego, CA. Our focus is on delivering multi-omics services to accelerate drug development and transform personalized medicine. Combining state-of-the-art mass spectrometry technology with advanced biocomputational services and multifaceted human health data, we enable biomarker...