Senior Director Medical Affairs

Senior Director, Medical Affairs — Oncology / Neurology Location: Boston, MA (Hybrid or Onsite) Reports to: VP, Global / US Medical Affairs Department: Medical Affairs Position Summary The Senior Director, Medical Affairs will serve as a strategic and scientific leader responsible for developing and executing the medical affairs strategy across the company’s oncology and/or neurology portfolio. This individual will provide medical and scientific leadership in support of late-stage development, product launches, and lifecycle management activities, ensuring alignment with corporate goals, compliance requirements, and evidence generation priorities. This position is ideal for an experienced medical leader who thrives in a dynamic, cross-functional environment and is passionate about translating scientific innovation into meaningful clinical and patient outcomes. Key Responsibilities Strategic & Scientific Leadership Develop and lead the integrated medical affairs strategy for assigned product(s) in oncology and/or neurology. Serve as a core member of cross-functional leadership teams, aligning medical objectives with clinical, regulatory, and commercial strategies. Oversee the creation and execution of medical plans , including evidence generation, KOL engagement, and medical communications. Partner with Clinical Development and Regulatory Affairs on label expansion , data generation , and scientific publication strategies . Medical Communications & Publications Oversee the development of scientific communication platforms , core claims documents , and scientific narratives . Guide publication planning and congress strategy (abstracts, posters, symposia). Provide medical input and review for promotional and non-promotional materials, ensuring scientific accuracy and regulatory compliance (FDA, PhRMA, OIG). KOL & External Engagement Build and maintain relationships with key opinion leaders (KOLs) , medical societies, and advocacy organizations. Lead advisory boards, investigator meetings, and educational initiatives to obtain insights and strengthen the company’s scientific reputation. Support Medical Science Liaisons (MSLs) and field teams through coaching, strategy, and scientific content development. Evidence Generation & Data Strategy Partner with R&D and clinical teams to identify real-world evidence (RWE) opportunities and investigator-initiated studies (IIS). Oversee post-marketing studies and ensure appropriate dissemination of safety and efficacy data. People Leadership Lead, mentor, and develop a high-performing medical affairs team (e.g., MSLs, medical directors, scientific communications, operations). Foster a culture of compliance, collaboration, and scientific excellence. Cross-Functional Collaboration Partner closely with Regulatory, Pharmacovigilance, Market Access, and Commercial to ensure consistent, scientifically sound messaging. Contribute to launch readiness and lifecycle management activities. Qualifications & Experience Education: MD, DO, or PhD (MD/PhD strongly preferred) in a biomedical discipline. Board certification or relevant therapeutic experience in oncology and/or neurology highly desirable. Experience: 10–15+ years of pharmaceutical/biotech experience, including at least 5 years in Medical Affairs leadership roles. Proven success in developing and executing global or regional medical strategies . Strong understanding of drug development, regulatory pathways (BLA/NDA), and post-marketing requirements. Experience in leading product launches and managing medical teams across the US and/or global regions. Demonstrated ability to build relationships with KOLs and external experts. Prior hands-on experience in oncology, neurology, or related therapeutic areas required. Skills & Attributes: Strategic thinker with strong operational and executional capability. Excellent communication, leadership, and influencing skills. Ability to thrive in fast-paced, evolving biotech environments. Deep knowledge of FDA, OIG, and PhRMA guidelines, as well as GCP and industry codes of practice. Compensation & Benefits (Typical Range) Competitive base salary: $250,000 – $300,000+ , commensurate with experience. Annual performance bonus and long-term incentive eligibility (equity/stock options). Comprehensive health benefits, 401(k), and flexible work arrangements. Example Company Snapshot (for context) This Boston-based biotech company is advancing a portfolio of innovative therapeutics in oncology and neurology , including late-stage assets with upcoming regulatory milestones. The company’s mission is to bring transformative therapies to patients with high unmet needs through a science-driven, patient-centered approach.