Remote Lead Software Engineer

Twin Health  At Twin Health, we empower people to improve and prevent chronic metabolic diseases, like type 2 diabetes and obesity, with a new standard of care. Twin Health is the only company applying AI Digital Twin technology exclusively toward metabolic health.  We start by building a dynamic model of each person’s metabolism — drawing on thousands of data points from CGMs, smartwatches, and meal logs — that maps their personal path to better health. Guided by a dedicated clinical care team, our members have lowered their A1C below the diabetes range, achieved lasting weight loss, and reduced or even eliminated medications, all while living healthier, happier lives. Our team at Twin Health is passionate, talented, and united by a shared purpose: to improve the metabolic health and happiness of our members. Twin has been recognized not only for our innovation but also for our culture, including: Innovator of the Year by the Employer Health Innovation Roundtable (EHIR), selected to CB Insights’ Digital Health 150, and named one of Newsweek’s Top Most Loved Workplace® . With more than $100 million raised in recent funding, including a $53 million Series E round in 2025 led by Maj Invest, and a $50 million investment in 2023 led by Temasek, Twin is scaling rapidly across the U.
Backed by leading venture firms like ICONIQ Growth, Sequoia, Sofina, Temasek, and Peak XV, we are building the most impactful digital health company in the world. Join us as we reinvent the standard of care in metabolic health.   We are seeking a Lead Software Engineer to join our Copilot team and play a key role in shaping the technical direction and execution of our new AI-powered platform. This platform is designed to optimize and enhance the efficiency of our clinical operations teams. This role offers a compelling opportunity at the intersection of backend engineering, healthcare technology, and system integrations. As a technical leader, you will drive architectural decisions, lead complex initiatives, and influence engineering best practices. You will work closely with AI, mobile, and other engineering teams, as well as clinical operations stakeholders, to streamline workflows and ultimately improve the member experience. Design, develop, and scale backend services and RESTful APIs using FastAPI (Python) and Spring Boot (Java). Architect and implement AI agents, including prompt engineering, evaluation, and continuous improvement workflows. Own end-to-end delivery of projects, including design, implementation, testing, deployment, and operational support. Manage and improve CI/CD pipelines to enable safe and rapid feature releases. Monitor, troubleshoot, and optimize system performance to support high throughput and rapid growth. Partner closely with Product, Design, DevOps, and AI/ML teams to align technical execution with Copilot product goals, and effectively communicate trade-offs and progress to stakeholders. Bachelor’s degree in Computer Science, Engineering, or related STEM field (Master’s preferred). ~6+ years of professional software engineering experience (backend or full-stack). ~ Strong proficiency in Python and/or Java, with hands-on experience building microservices using FastAPI and/or Spring Boot. ~ Deep understanding of API design (REST), authentication/authorization (OAuth2, JWT), and data modeling. ~ Practical experience working with AI systems, including prompt engineering or AI service integration. ~ Demonstrated leadership experience through prior projects or roles. ~ Strong debugging and performance optimization skills in production environments ~ Experience with AWS, Kubernetes, and CI/CD pipelines is a plus ~ Prior experience working on AI-native products or internal developer platforms is a plus. ~ This remote opportunity based out of the U.
We are unable to sponsor or take over sponsorship of an employment Visa at this time. Twin has an ambitious vision to empower people to live healthier and happier lives, and to achieve this purpose, we need the very best people to enhance our cutting-edge technology and medical science, deliver the best possible care, and turn our passion into value for our members, partners and investors. A competitive compensation package in line with leading technology companies ~ A remote and accomplished global team ~ Opportunity for equity participation  ~ 100% Employer sponsored healthcare, dental, and vision for you, and 80% coverage for your family; Health Savings Account and Flexible Spending Account options ~401k retirement savings plan We will never ask you to complete a text interview or request financial details during the interview process.