核药科学家 — 恒瑞-全球精英计划
3 weeks ago
工作地点：天津 主要职责：
1. 设计与执行科学实验，支持放射性药物的发现与开发，包括新型放射性标记化合物的合成、纯化与表征。独立或合作完成实验数据的生成、分析与解读，推动项目进展。
2. 确保合规性，遵循行业与监管标准（如SOP、GLP、GMP），维持放射性药物研发与生产的严格质量控制。
3. 操作与维护专业设备（如放射性标记模块、高效液相色谱仪、γ计数器），支持核医学的临床前与转化研究。
4. 与跨职能团队（内外部）协作，推动放射性药物发现、放射性配体疗法（RLT）与诊疗一体化领域的创新。
5. 跟踪核医学、放射化学与分子影像领域的前沿技术，优化研究方法并拓展治疗应用。
任职要求：
1. 博士学历，专业方向为放射性药物科学、药物化学、分子影像或相关领域。
2. 具备扎实的药物发现/开发背景，有肿瘤学、放射化学或靶向放射性核素治疗经验者优先。
3. 精通实验室技术，包括放射性药物合成、放射性标记（如⁶⁸Ga、¹⁷⁷Lu、²²⁵Ac）与分析表征（HPLC、TLC、质谱）。
4. 熟练使用英语（书面与口语），支持全球协作与法规文件撰写。
5. 具备科学文献调研能力，能将前沿研究整合至实验设计中。
6. 优秀的沟通与团队协作能力，适应多学科研究环境。
Key Responsibilities:
1. Design and execute scientific experiments to support the discovery and development of radiopharmaceuticals, including the synthesis, purification, and characterization of novel radiolabeled compounds. Independently or collaboratively generate, analyze, and interpret experimental data to advance project objectives.
2. Ensure compliance with industry and regulatory standards (e.g., SOPs, GLP, GMP) to maintain rigorous quality control in radiopharmaceutical research and production.
3. Operate and maintain specialized equipment (e.g., radiolabeling modules, HPLC, gamma counters) to support preclinical and translational research in nuclear medicine.
4. Collaborate with cross-functional teams (internal and external) to drive innovation in radiopharmaceutical discovery, radioligand therapy (RLT), and theranostics.
5. Stay abreast of emerging technologies in nuclear medicine, radiochemistry, and molecular imaging to enhance research methodologies and therapeutic applications.
Qualifications & Requirements :
1. Ph.D. degree in Radiopharmaceutical Sciences, Medicinal Chemistry, Molecular Imaging, or a related discipline.
2. Strong background in drug discovery/development, with preferred experience in oncology, radiochemistry, or targeted radionuclide therapy.
3. Expertise in laboratory techniques relevant to radiopharmaceutical synthesis, radiolabeling (e.g., ⁶⁸Ga, ¹⁷⁷Lu, ²²⁵Ac), and analytical characterization (HPLC, TLC, mass spectrometry).
4. Proficiency in English (both written and spoken) to support global collaboration and regulatory documentation.
5. Demonstrated ability in scientific literature review to integrate cutting-edge research into experimental design.
6. Excellent communication and teamwork skills to effectively collaborate in a multidisciplinary research environment.
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