Research Scientist I

7 days ago

Beverly Hills CA, United States CEDARS-SINAI Full time

Job Description Principal Investigator, Joshua Burda, PhD, is looking for a Postdoctoral Scientist to join the team
The Burda Lab explores how glia respond to injuries and disorders of the CNS and how these responses impact on neural repair, regeneration and neurological recovery. As a Postdoc, you will participate in research studies and perform lab techniques under the guidance of the Principal Investigator. The ideal candidate will investigate astrocyte-mediated molecular mechanisms underlying neural tissue remodeling, inflammation and regenerative plasticity of neural circuits after central nervous system (CNS) injury and in disease. Our research aims to make use of multiple mouse models of nervous system injury and employ cell type-specific in vivo molecular manipulations, single cell RNA and ATAC sequencing, mouse transgenics, primary neuron, astrocyte and microglia culture, molecular biology, protein biochemistry, neuroanatomical tract tracing, histology, microscopy, and biobehavioral assessments in mouse models of CNS injury and degeneration.
Are you ready to be a part of breakthrough research?
Burda and other Research Scientists, the Postdoctoral Scientist will perform routine and complex laboratory procedures throughout training period. Analyzes and interprets data. Postdoctoral Scientists in the Burda Lab also benefit from the groups’ well-established and ongoing collaborations with neighboring UCLA David Geffen School of Medicine and Brain Research Institute Investigators.
May assist in the preparation of grant proposals, but is not responsible for generating grant funds.
May develop, adapt, and implement new research techniques and protocols.
Analyzes interpret, summarizes, and compiles data.
Performs routine and complex laboratory procedures throughout the training period.
Operates and maintains equipment and instruments.
May observe MD-patient or MD-human research subject interactions as it pertains directly to research being performed.  
Doctorate (MD, PhD, VMD or DDS) in an area related to the field of research specialization is required.

Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment.
Works independently on research projects designed by a mentor (typically the PI) within area of specialization.
Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment.
Knowledge of safety standards and maintenance of specialized equipment.
Experience with rodent surgery is preferred, but not required.
R and/or Python programming language basics (preferred, but not required).
Light microscopy (e.g. laser-scanning confocal and epifluorescence)
Qualitative and quantitative analysis of cells and/or tissues.
A range of wet lab techniques including nucleic acid and/or protein biochemistry
A range of tissue processing and histological preparations for cellular and molecular analysis.
Collaborate with PI in preparation of Postdoctoral Fellowship applications.  
Cedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents.
Cedars-Sinai is one of the largest nonprofit academic medical centers in the U.with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most.
Working Title : Postdoctoral Scientist- Burda Lab - Center for Neural Science and Medicine
Department : Research - BMS
Business Entity : Cedars-Sinai Medical Center
Academic / Research
Postdoctoral Scholar
Overtime Status : EXEMPT
Primary Shift : Day
Shift Duration : 8 hour

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