Principal Scientist

Principal Investigator – Proteomics Kelly® Science & Clinical is seeking a CRO Principal Investigator, Proteomics for a direct-hire position at a cutting‑edge client in San Diego, CA . If you’re passionate about bringing the latest scientific discoveries to life and are ready to take the next step in your career, trust The Experts at Hiring Experts. Salary: $135,000 - $185,000 Schedule: Full‑time, On‑site Overview This client is an industry‑leading company that’s transforming personalized medicine through multi‑omics services. By integrating advanced mass spectrometry, biocomputational tools, and human health data, the Client enables rapid biomarker discovery and deeper biological insights. The collaborative team of scientists, clinicians, and engineers is committed to scientific rigor and innovation, enhancing the precision and efficacy of treatments across therapeutic areas. In this role, you will lead complex proteomics projects, drive scientific innovation, and manage client relationships in a regulated CRO environment. You’ll be responsible for integrating multi‑omics data, mentoring teams, and setting the benchmark for scientific excellence. Responsibilities: Collaborate with top‑tier experts to promote personal and professional growth through enriching training initiatives. Manage projects between clients and internal wet‑ and dry‑lab teams to ensure deliverables are met. Develop research strategies, study plans, and reports. Review mass spectrometry spectra and perform compound identification. Ensure results meet quality and regulatory standards. Compile data and results into final presentations and data packages. Prioritize and organize multiple projects to meet timelines and deliverables. Interpret scientific results and stay current with literature and technological advancements. Manage 15+ client programs, participate in study design, and orchestrate seamless handoff of information between clients and laboratory personnel. Qualifications: PhD/MD in chemistry, biochemistry, biology, pharmacology, or related life science discipline; or equivalent experience (BS + 10 years, MS + 5 years). Minimum 5 years of experience in CRO, pharmaceuticals, or biotechnology. Expertise in LC‑MS/MS instrumentation (Orbitrap, Q‑TOF, timsTOF) and data analysis pipelines (DDA, DIA, PRM, MRM/SRM, TMT/iTRAQ, PTM). Proven ability to design and execute complex proteomics experiments. 5 years of leadership experience managing scientific projects and teams. Experience in client‑facing roles and cross‑functional collaboration. Exposure to metabolomics and proteomics methodologies. Strong analytical mindset and ability to interpret complex data. Excellent communication skills for scientific presentations and mentoring. Collaborative spirit and ability to work with multidisciplinary teams. Detail‑oriented and committed to producing accurate, reliable results. Up‑to‑date with advancements in precision medicine. What happens next: Once you apply, you’ll proceed to next steps if your skills and experience look like a good fit. But don’t worry – even if this position doesn’t work out, you’re still in our network. That means our team of expert Science & Clinical recruiters will have access to your profile, making your opportunities limitless. As part of our promise to talent, Kelly supports those who work with us through a variety of benefits, perks, and work‑related resources. Kelly offers eligible employees voluntary benefit plans including medical, dental, vision, telemedicine, term life, whole life, accident insurance, critical illness, a legal plan, and short‑term disability. As a Kelly employee, you will have access to a retirement savings plan, service bonus and holiday pay plans (earn up to eight paid holidays per benefit year), and a transit spending account. In addition, employees are entitled to earn paid sick leave under the applicable state or local plan. Click here (https://www.mykelly.com/help-support-working-with-kelly-us/#Benefits) for more information on benefits and perks that may be available to you as a member of the Kelly Talent Community. Why Kelly ® Science & Clinical? Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire industry experts just like you. Our team creates expert talent solutions to solve the world’s most critical challenges. Every day, we match science professionals with dream jobs that fit their skills, interests, and career goals—it’s the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background and education in science, so we know a thing or two about the science market and how to get your expertise noticed. About Kelly Work changes everything. And at Kelly, we’re obsessed with where it can take you. To us, it’s about more than simply accepting your next job opportunity. It’s the fuel that powers every next step of your life. It’s the ripple effect that changes and improves everything for your family, your community, and the world. Which is why, here at Kelly, we are dedicated to providing you with limitless opportunities to enrich your life—just ask the 300,000 people we employ each year. Kelly is committed to providing equal employment opportunities to all qualified employees and applicants regardless of race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or any other legally protected status, and we take affirmative action to recruit, employ, and advance qualified individuals with disabilities and protected veterans in the workforce. Requests for accommodation related to our application process can be directed to the Kelly Human Resource Knowledge Center. Kelly complies with the requirements of California’s state and local Fair Chance laws. A conviction does not automatically bar individuals from employment. Kelly participates in E‑Verify and will provide the federal government with your Form I‑9 information to confirm that you are authorized to work in the U.S. Kelly Services is proud to be an Equal Employment Opportunity and Affirmative Action employer. We welcome, value, and embrace diversity at all levels and are committed to building a team that is inclusive of a variety of backgrounds, communities, perspectives, and abilities. At Kelly, we believe that the more inclusive we are, the better services we can provide. Requests for accommodation related to our application process can be directed to Kelly’s Human Resource Knowledge Center. Kelly complies with the requirements of California’s state and local Fair Chance laws. A conviction does not automatically bar individuals from employment. #J-18808-Ljbffr