Director, Translational Medicine

Join to apply for the Director, Translational Medicine role at Vor Bio Get AI-powered advice on this job and more exclusive features. Join Us in Tackling Autoimmune Disease at Its Root At Vor, we believe science can do more than manage symptoms. It can change the course of disease. By advancing telitacicept, a first- and potentially best-in-class dual BAFF/APRIL inhibitor, we are silencing upstream survival signals and stopping downstream autoimmune cascades. Together, we are addressing disease at its root cause and rewriting what is possible for patients worldwide. When you join Vor, you’re not just working on a medicine. You’re part of a mission to redefine the future of autoimmune care. Why Work at Vor? Impact: Contribute directly to a medicine with best‑in‑disease Phase 3 results in myasthenia gravis and expansion into multiple autoimmune diseases. Growth: Be part of a rapidly scaling company with opportunities to grow your career in science, clinical development, commercial strategy, and beyond. Innovation: Work on a platform with potential beyond one indication — a therapy that has already shown consistent results across lupus, IgA nephropathy, and Sjögren’s syndrome. Belonging: Join a culture where every voice is heard, and where our shared mission unites us across functions and geographies. We are seeking a visionary and scientifically driven Director of Translational Medicine to lead the strategic integration of preclinical and clinical research, accelerating the development of innovative therapies from bench to bedside. This leadership role bridges discovery science and clinical application, ensuring that our R&D pipeline is informed by cutting‑edge translational insights and patient‑centric strategies. Key Responsibilities Strategic Leadership: Define and execute the translational medicine strategy across therapeutic programs, aligning with corporate R&D goals. Biomarker Development: Oversee the identification, validation, and implementation of predictive, pharmacodynamic, and safety biomarkers. Clinical‑Preclinical Integration: Translate preclinical findings into clinical hypotheses and study designs; ensure bidirectional flow of insights between lab and clinic. Cross‑Functional Collaboration: Partner with discovery, preclinical toxicology, clinical development, regulatory, bioinformatics, and commercial teams to drive data‑informed decision‑making. External Engagement: Build and maintain relationships with academic collaborators, CROs, consortia, and regulatory bodies to advance translational objectives. Data Strategy: Guide the integration of multi‑omics, imaging, and real‑world data to inform patient stratification and therapeutic response. Team Leadership: Mentor and lead a high‑performing team of translational scientists and project leads. Qualifications PhD, MD, or MD/PhD in a relevant scientific discipline (e.g., immunology, oncology, neuroscience, pharmacology). 10+ years of experience in translational medicine, clinical development, or related R&D roles in biotech/pharma. Proven track record of advancing drug candidates through late phase clinical development (Phase II–III). Deep understanding of biomarker science, clinical trial design, and regulatory considerations. Strong leadership, communication, and cross‑functional collaboration skills. Experience with omics technologies, bioinformatics, and data integration is highly desirable. Preferred Attributes Therapeutic area expertise in autoimmune, immunology, and/or rare diseases. Experience working in fast‑paced, innovative biotech environments. Familiarity with regulatory submissions (e.g., IND, CTA, BLA) and companion diagnostics development. The salary range for this position is expected to be between $225,854 and $239,439 per year. Individual pay may vary based on multiple factors including but not limited to relevant job‑related skills, experience, education or training, market factors, and work location. At Vor, we support our team with robust benefits, including comprehensive health coverage, flexible paid time off, generous parental leave, and a competitive 401(k). From education assistance to wellness resources and financial security, we invest in your well‑being so you can thrive at work and beyond. As an equal opportunity employer, we at Vor Bio know that diversity inspires innovation, inclusiveness, and creativity. We invite you to come as you are. All applicants will be considered for employment agnostic to race, age, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. Please visit our website at https://www.vorbio.com/ for more information. Seniority level: Director Employment type: Full‑time Job function: Other #J-18808-Ljbffr