Director, Manufacturing
4 weeks ago
Director, Manufacturing – Neurogene Inc. Join to apply for the Director, Manufacturing role at Neurogene Inc. Overview The mission of Neurogene is to treat devastating neurological diseases to improve the lives of patients and families impacted by these rare diseases. Neurogene is developing novel approaches and treatments to address the limitations of conventional gene therapy in central nervous system disorders. This includes selecting a delivery approach to maximize distribution to target tissues and designing products to maximize potency and purity for an optimized efficacy and safety profile. The Company’s novel and proprietary EXACT transgene regulation platform technology allows for the delivery of therapeutic levels while limiting transgene toxicity associated with conventional gene therapy. Neurogene has constructed a state‑of‑the‑art gene therapy manufacturing facility in Houston, Texas. CGMP production of NGN‑401 was conducted in this facility and will support pivotal clinical development activities. This transformative work is driven by our highly collaborative people who come together each day to bring us closer to achieving our mission. As an employee of Neurogene, you will be part of building a culture that honors patient and caregiver mindsets and nurtures innovation, creative problem solving and a strong sense of purpose. Responsibilities Provide strategic and operational leadership of GMP Manufacturing operations with responsibility for ensuring uninterrupted production of clinical and commercial gene therapy products. Lead, develop, and mentor a cross‑functional team of manufacturing staff and managers to deliver on production goals, operational excellence, and compliance. Serve as a key contributor to the manufacturing leadership team, ensuring alignment with overall company objectives and timelines. Act as primary manufacturing liaison with cross‑functional teams including Quality, Regulatory, Analytical Development, Supply Chain, and Process Development to support tech transfers, deviations, CAPAs, and continuous improvement initiatives. Drive implementation of lean manufacturing principles and quality by design (QbD) strategies to enhance process robustness and reduce variability. Oversee execution and review of batch records, ensuring compliance with cGMPs and internal quality standards. Support inspection readiness activities and directly interface with regulatory agencies and partners as required. Contribute to manufacturing strategy development, budgeting, headcount planning, capital projects, and new technology implementation. Oversee execution of the Process Performance Qualification (PPQ) strategy and associated manufacturing campaign, ensuring alignment with process validation plans, quality system requirements, and regulatory expectations. Represent Manufacturing in CMC regulatory submissions and participate in preparation of BLA/MAA filings. Ensure documentation is completed to meet quality systems requirements. Work with Quality Assurance to achieve and maintain GMP readiness and compliance in manufacturing. Participate in facility safety programs. Hire, train, and supervise direct reports, and encourage continuing education and development. Essential Details Work Schedule: Day shift (some off‑shift hours: early mornings, late evenings/nights, and weekends if necessary) Travel:
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Operations Director
4 weeks ago
Houston, United States Clayton Services Full timeOperations Director - Food ManufacturingClayton Services is searching for an Operations Director - Food Manufacturing to join a thriving company in Houston, Texas. The Operations Director - Food Manufacturing will be responsible for overseeing daily operations across multiple plants, ensuring compliance with food safety regulations, driving efficiency and...
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Operations Director
1 week ago
Houston, United States Clayton Services Full timeClayton Services is searching for an Operations Director - Food Manufacturing to join a thriving company in Houston, Texas. The Operations Director - Food Manufacturing will be responsible for overseeing daily operations across multiple plants, ensuring compliance with food safety regulations, driving efficiency and profitability, and fostering a...
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Houston, United States Houston Staffing Full timeOperations Consulting Role at PwCAt PwC, our people in operations consulting specialize in providing consulting services on optimizing operational efficiency and effectiveness. These individuals analyze client needs, develop operational strategies, and offer guidance and support to help clients streamline processes, improve productivity, and drive business...
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Director of Manufacturing Science
4 weeks ago
Houston, United States JCW Group Full timeOverviewOur client is actively looking for a Director of Manufacturing Science & Technology. This is an on-site position in Houston TX. Relocation assistance offered.QualificationsB.S with prior Director level experience within pharma/biotech/medical device industry10+years of experience in process development, process validation or manufacturing sciences5+...
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Houston, United States Rogers-O'Brien Construction Full timeDirector of Business Development – Advanced Manufacturing Join Rogers‑O’Brien Construction as a Director of Business Development in the Advanced Manufacturing sector. Located in Houston, this exempt‑executive full‑time role reports to regional leadership. What You’ll Do Lead and collaborate with the business development team and regional...
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Houston, United States University of Houston Full timeDirector of Texas Manufacturing Assistance Center Department: Tx Mfg Assis Cntr Salary: Commensurate with Experience/Education Director of Texas Manufacturing Assistance Center (TMAC) which provides business/process consulting and training assistance to manufacturing and related businesses. Responsible for planning, administration, and supervision of the...
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Sr Director-Manufacturing
2 weeks ago
Houston, United States Aventiv Technologies Full timeJob OverviewSr Director-Manufacturing at Aventiv Technologies. This role oversees management of all areas of manufacturing and facilities operations including supply chain, inventory, assembly, quality assurance, shipping and receiving, and reverse logistics to produce and ship products on schedule and within quality standards and cost objectives.Job...
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Director, Subcontracting Manufacturing
1 week ago
Houston, Texas, United States Konecranes Full time $80,000 - $120,000 per yearCompany DescriptionAt Konecranes, we believe that great customer experience is built on the people behind the Konecranes name. Everything we do, we do with passion and drive. We believe diversity drives business success and is the foundation for our growth. We welcome different backgrounds and skills that enrich our community and we promote a place where we...
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Director of Manufacturing Accounting
2 weeks ago
Houston, United States CFS Full timeA leading staffing agency in Houston, TX is seeking a Director of Accounting to lead the accounting team and provide strategic insights. This highly visible leadership role requires a Bachelor's in Accounting and CPA, alongside 6–10 years of experience in manufacturing and distribution accounting. The ideal candidate will enhance processes and ensure...
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Houston, United States Re:Build Manufacturing Full timeDirector Of Business Development Custom Process Equipment EnergyAt Re:Build Optimation, we specialize in delivering custom-engineered process equipment and automated systems to clients across the globe. With 40 years of experience in complex chemical process systems, we have built a reputation for precision, reliability, and innovation. Our multidisciplinary...
