Principal Cell Process Biochemist

Join to apply for the Principal Cell Process Biochemist role at Therakos Healthcare Limited. The Principal Cell Process Biochemist will lead and support Therakos research & development initiatives, optimizing and characterizing biochemical processes for cell-based therapies. You will work to understand biochemical reactions and cellular pathways, design bioreactor systems, develop biomaterials and microfluidics, and optimize biochemical processes to produce therapeutic human cells. The ideal candidate brings deep biochemical insight into cellular function, cell therapy process design, and subject‑matter expertise to shape our cell‑based therapeutics initiatives from early discovery through clinical development. Job Requirements PhD in Biochemistry, Cell Biology, Bioengineering or related field with 5+ years industry/academic research experience or MS with 8+ years of relevant experience. Strong understanding of cellular biochemistry including metabolism, protein expression & stress response. Hands‑on experience with cell culture, media optimization & bioreactor operation. Experience in cell therapy, CAR‑T or stem cell process development. Knowledge of cell harvest, lysis & purification methods. Strong understanding of critical quality attributes in biologics/cell manufacturing. Strong publication and/or patent record in relevant areas is a plus. Experience with regulatory and translational aspects of cellular technologies is a plus. Excellent communication and presence; comfortable presenting to executive teams, boards, and external stakeholders & scientific symposia. Job Responsibilities Lead at the intersection of science & engineering in the design & development of novel cell manufacturing platform technologies. Analyze and optimize cell metabolism, growth kinetics, and product yield using biochemical and systems biology approaches. Design and implement in vitro and in vivo studies examining the effects of our cell therapies & platforms on biological systems. Support process characterization and validation activities. Collaborate with cross‑functional teams—engineering, quality & operations—to ensure seamless tech transfer and product/process integration. Design and execute experiments using Design of Experiments (DoE) and interpret complex data sets to drive process decisions. Prepare technical reports, SOPs, and documentation to support regulatory submissions (e.g., IND, BLA). Serve as a scientific leader and mentor, supporting the development of junior scientists and fostering a culture of innovation. Stay at the forefront of the field through publication, conference participation, and collaboration with academic partners. Partner with other functional leaders in Clinical, Regulatory, Engineering, Business Development to advance programs and shape strategy. Benefits Life/AD&D Short‑ and Long‑Term Disability 401(K) with large company match Health Saving Account (HSA) and Flexible Spending Account (FSA) with company match Wellness Program Employee Assistance Program (EAP) Generous Paid Time Off (PTO) Onsite in Franklin, TN with flexible core hours Disclaimer: The included statements are intended to describe the general nature and level of work being performed by employees assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of employees assigned to this position. Seniority level: Mid‑Senior level Employment type: Full‑time Job function: Science, Manufacturing, and Research Industries: Medical Equipment Manufacturing #J-18808-Ljbffr