Oncology Early Stage Clinical Scientist

Oncology Early Stage Clinical Scientist (Director, Non-MD) Join Pfizer as an Oncology Early Stage Clinical Scientist (Director, Non-MD). This role leads and coordinates the development of multiple studies of novel biological and small molecules for first‑in‑human (FIH), proof‑of‑mechanism (POM), early signs of efficacy (ESOE), and proof‑of‑concept (POC) studies in oncology. POSITION SUMMARY Work closely with the Global Development Lead and the development team to establish, lead, coordinate, and execute the early oncology clinical development plan(s). Lead the development of the clinical protocol and serve as an individual contributor on clinical teams to meet enrollment and study delivery timelines. Collaborate with interdisciplinary teams (Research Units, Biostatistics, Clinical Pharmacology, Precision Medicine, Digital Medicine) to ensure the full scope of Oncology Early Stage Development is represented. POSITION RESPONSIBILITIES Partner closely with the Global Development Lead (GDL) to execute the clinical development strategy and plan for assigned molecule(s)/indication(s). Provide scientific leadership and execution of clinical studies, delivering high quality trial execution, safety assessment, and interpretation of clinical study results. Support execution for all FIH programs through proof‑of‑concept. Set the clinical data review strategy, ensuring quality data, review emerging clinical data and trends, and present relevant data to appropriate teams, governance bodies, and stakeholders. Conduct data review, analysis and interpretation of clinical trials data together with GDL, Clinical Safety, and Biostatistics. Serve as technical resource for clinical issues raised by internal and external collaborators, investigators, consultants, and contractors. Support development of publications, abstracts, and presentations. Participate in project teams to assist in the implementation of clinical development and contribute to key milestones (e.g., start‑up and delivery of ESOE and POC trials). Lead preparation of clinical protocols and support critical documents including clinical development plans, INDs, annual reports, CSRs, investigator brochures, statistical analysis plans, and regulatory documents. Foster a transparent environment that builds strong partnerships and mutual trust among teams and therapeutic areas. Coordinate with other clinical research activities within Oncology Research Development (ORD) and the broader Worldwide Research and Development (WRD) organization. Develop effective collaborations with key internal and external partners, such as project leaders, research units, biostatistics, regulatory affairs, clinical pharmacology, human genetics, translational oncology, precision medicine, and development operations. Partner with Translational Oncology and Biomarker teams to integrate biomarker plans into relevant programs for early efficacy signs and POC, and patient stratification. Establish and support relationships with external experts, consultants, key opinion leaders, regulators, and investigator networks to integrate the latest clinical thinking and guidelines into development plans and study designs, and manage study recruitment, analysis, interpretation, and presentation of results. Maintain up‑to‑date knowledge of scientific and clinical literature in relevant therapeutic areas, including key clinical development issues. Perform other duties as assigned related to clinical programs. Support functional area priorities and contribute to or lead departmental initiatives as requested. MINIMUM QUALIFICATIONS / KEY SKILLS Relevant PhD or PharmD and a minimum of 5 years of experience in a similar role in industry/CRO. MS and a minimum of 7 years of experience in a similar role in industry/CRO. BA/BS and a minimum of 10 years of experience in a similar role in industry/CRO. Clinical research experience in Phase 1 oncology, on the side of the sponsor leading studies. Experience in or strong understanding of oncology drug development, especially in early development. Strong knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations. Strong scientific writing skills and communication skills (written and verbal). Clinical document writing experience (protocol, investigational new drug (IND) application, investigator brochure (IB)), and understanding complex data analysis. Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations. Experience working with and solid understanding of related disciplines (clinical operations, safety, biostatistics, regulatory, study management, pre‑clinical, pharmacology, quality assurance). Experience building consensus and driving change across all levels of the organization including senior management. Data listing review experience. Critical thinker, with experience working collaboratively in a fast‑paced, team‑based matrix environment as well as when working independently. Experience performing complex data analyses using JReview, SpotFire, SOCs‑PRO or other similar platform. PREFERRED QUALIFICATIONS Experience leading a team. PHYSICAL/MENTAL REQUIREMENTS Perform complex data analysis. NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS 5-10% travel. WORK LOCATION – HYBRID This is a hybrid role requiring you to live within commuting distance and work on‑site an average of 2.5 days per week. SALARY The annual base salary ranges from $169,700 to $282,900. The position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20% of the base salary and participation in the share‑based long‑term incentive program. BENEFITS Pfizer offers a comprehensive benefits program that includes 401(k) with company match, retirement savings contributions, paid vacation, holidays, personal days, caregiver/parental leave, medical benefits (medical, prescription drug, dental, vision), and more. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer complies with all applicable nondiscrimination laws and with the Immigration and Nationality Act and IRCA. Pfizer is an E‑Verify employer. This position requires permanent work authorization in the United States. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. #J-18808-Ljbffr