Commercial Supply Chain Associate Director

Job Description General Summary This role will lead and drive the Sales and Operations Planning (S&OP) process for Casgevy, a commercially launched product within Vertex's Cell and Gene Therapy portfolio. This is a critical role within the Vertex Supply Chain, that includes the ability to perform complex modeling, utilizing assumptions, demand and capacity to meet both short- and long-term requirements. The Associate Director will be responsible for working with the commercial team to align assumptions and the demand plan, External Manufacturing to work with CDMO's to align capacity assumptions, Finance, Materials, Quality Control and Regulatory that will culminate in the monthly S&OP process. This role will be responsible for establishing and communicating key assumptions, as well as scenario management which often requires modeling outside of the current system to understand capacity / demand alignment and financial impact. Additionally, the AD will oversee several Key Performance Indicators (KPI's) that are managed within the S&OP process and identifying areas for improvement. The Associate Director will use the dynamic capacity model to recommend scheduling strategies, future capacity needs, and capacity utilization strategies based on unexpected events (i.e. patient withdrawals, suite downtime, etc.). The selected individual will build and lead the monthly S&OP meetings and play an integral role in the development and communication of Vertex's Cell and Gene Therapy assets. As the Cell and Gene Therapy Supply Chain matures at Vertex, this role will be responsible for the implementation of a new planning tool that will systematize the planning process. This involves working cross-functionality with finance, external manufacturing and materials management to identify and document requirements, and working with the integration team to implement. The output of this implementation will be an integrated plan that takes demand and capacity to create an output that will be implemented across CDMO's, materials suppliers, testing sites and for financial purposes. Key Duties and Responsibilities Lead development of a commercial capacity model across multiple CMOs. Maintain, utilize, and improve upon a capacity model that is dynamic, allowing for long range planning, situational planning, and analysis of unexpected events. Ability to perform detailed modeling (Excel), analyze and present data, and systematize as needed Excellent knowledge of Supply Chain systems Ability to lead teams, both directly (dotted line) and cross-functionally Integrate the capacity model into the manufacturing strategy, allowing for scenario planning and scheduling. Integrate the capacity model into the commercial strategy, allowing for direct connection with demand forecasting and scheduling tools. Integrate the capacity model into the COGS model, allowing for direct impact assessment of COGS due to any capacity assumption changes. Lead S&OP meetings to align demand, capacity and assumptions. Excellent interpersonal, verbal and written communication skills Anticipate future industry trends and keep abreast with a strong foundation of knowledge of manufacturing, development, and supply Knowledge and Skills Bachelor's degree in a scientific or business discipline preferred, or equivalent years of relevant experience 8+ years of experience in Manufacturing and Supply Chain Management; experience in Cell and Gene Therapy is a plus. Proven ability to manage multiple projects with high degree of effectiveness Possesses a distinguished record of delivering on critical project goals and moving projects forward Exhibits robust knowledge across supply chain disciplines Demonstrates strong aptitude for managing and motivating others and building team unity Proven ability to communicate clearly and concisely (written/oral) with all levels of the company Good understanding of the cell and gene therapy and biotech industry and market High level understanding of GMP processes and regulatory requirements Ability to effectively plan, prioritize, execute, follow up and anticipate challenges Results orientated with strong sense of urgency to mitigate risk and close issues Knowledge of systems with skills and proficiency to download and analyze data Ability to communicate complex problems and necessary decision points both visually and verbally Education and Experience Bachelor's degree in a scientific or business discipline Typically requires 8 years of experience or the equivalent combination of education and experience Pay Range $149,300 - $224,000 Disclosure Statement The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status In this Hybrid-Eligible role, you can choose to be designated as: Hybrid: work remotely up to two days per week; or select On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com #J-18808-Ljbffr