Associate Scientist I- Cell and Gene Therapy

3 weeks ago


San Diego, United States Kyowa Kirin, Inc.- U.S. Full time

Associate Scientist I – Cell and Gene Therapy Join Kyowa Kirin, Inc.- U.S. as an Associate Scientist in the Cell and Gene Therapy discovery core function. We work in a fast‑growing, innovative environment to develop next‑generation therapies across multiple disease areas. Summary The Associate Scientist will support Kyowa Kirin’s cell therapy pipeline programs. With a strong collaborative focus, you will play a key role in developing new technologies, managing projects, and providing science expertise to enhance our cell and gene therapy portfolio. Essential Functions Support pipeline projects by enabling gene editing and generating novel molecular workflows. Serve as a Project Lead for technology‑themed projects when needed. Identify, evaluate, and implement new gene‑editing technologies. Contribute scientific and technical knowledge to project and support teams. Design, initiate, and optimize molecular, cellular, and analytical methods for RTO, In Vivo Phamacology, and Technical Ops teams. Maintain regulatory compliance, prepare documentation for reviews, patent applications, publications, and biosafety protocols. Present research findings at project meetings and record experiments in notebooks and databases. Requirements BS required; MA/MS preferred in a related discipline. 8+ years of hands‑on experience in cell and gene therapy techniques with deep expertise in gene editing. Extensive experience with CRISPR, base editing, prime editing, or transposase/recombinase‑based editing. Strong background in NGS, molecular biology, and cloning. Cell culture expertise with HSCs, iPSCs, and CAR‑T cells. Experience in high‑throughput screening, CAR design, and assay development. Knowledge of antibody/protein engineering, purification, and virus production. Proficient in MS Office Suite. Technical Skills CRISPR and guide RNA design; indel analysis; knock‑in/out assays; NGS; ddPCR. Cellular, molecular, and immunological techniques: cloning, ELISA, multi‑color flow cytometry, in‑vitro functional assays. Cell engineering processes including cell line generation and therapeutic cell development. Cell culture of primary cells, iPSCs, HSCs, and cell lines from multiple species. Cell characterization techniques: flow cytometry, FACS, MACS, single‑cell isolation. Antibody/protein production, purification, and analysis. Compensation The anticipated salary range for this position is $120,000 to $125,000. Final salary will be based on experience, qualifications, and market factors. Benefits 401(k) with company matching Discretionary profit sharing Annual bonus program Generous PTO and holiday schedule, including summer and winter shut‑down, sick days, and volunteer days Health, dental, vision, and prescription drug coverage HSA & FSA programs Well‑being and work/life programs Life & disability insurance Concierge service and pet insurance Tuition assistance Employee referral awards Location La Jolla, CA (Office‑based) Recruitment & Staffing Agencies Kyowa Kirin does not accept agency resumes unless contacted directly by internal Talent Acquisition. Please do not forward resumes to company employees or other locations. Equal Employment Opportunity Statement Kyowa Kirin North America, Inc. is committed to providing equal employment opportunity to all qualified persons without regard to race, religion, creed, color, pregnancy, sex, age, national origin, disability, genetic trait or predisposition, veteran status, marital status, sexual orientation or affection preference, citizenship status, or any other category protected by law. Privacy and Data Protection When you apply to a job on this site, your personal data will be processed for recruiting purposes by Kyowa Kirin, Inc. (“Controller”) in accordance with applicable privacy laws. For more information, contact us at usprivacyoffice@kyowakirin.com. #J-18808-Ljbffr



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