Lead Scientist, Discovery Biology

Lead Scientist, Discovery BiologyAbout the RoleWe are seeking a highly motivated Scientist to join our Discovery Biology team and drive translational biomarker strategy in one of our renal programs. This individual will play a key role in developing, validating, and implementing biomarker assays to support clinical trials, with a focus on renal physiology and related disease areas.ResponsibilitiesDesign and execute in vitro and in vivo studies to identify and validate novel biomarkers and elucidate mechanisms of action for GondolaBio’s therapeutic candidates.Develop, optimize, and validate biomarker assays (molecular, cellular, immunological) using mouse and human-derived samples to support translational research.Provide scientific and technical leadership in various biomarker platforms and evaluate emerging biomarker technologies for clinical relevance and technical performance; integrate innovative approaches into ongoing programs.Analyze and interpret biomarker data from preclinical and clinical studies; communicate findings clearly to cross-functional teams.Implement biomarker plans in clinical protocols and lab manuals; oversee assay execution at CROs and external partners under Good Clinical Practice (GCP).Partner effectively with internal and external stakeholders and maintain well-documented research records.RequirementsPh.D. in Molecular/Cell Biology, Immunology, or a related discipline with 2+ years of relevant industry experience, or B.S./M.S. with 5+ years of industry experience.Strong expertise in utilizing in vitro experimental techniques as they pertain to a biomarker strategy, including flow cytometry, ligand binding assays, primary cell culture and functional in vitro assays, and immunohistochemistry (IHC).Demonstrated ability to rigorously analyze, interpret, and present complex datasets.Strong problem-solving, communication, and cross-functional collaboration skills.Proficiency with high-dimensional data analysis for gene expression, WGS, cfDNA, or proteomics datasets.Experience with advanced technologies such as mass spectrometry, PEAs, automated IHC, and Incucyte live-cell imaging.Experience working with contract research organizations and third-party labs.What We OfferPatient Days, where we hear directly from individuals living with the conditions we are seeking to impact throughout the year and learn how we can improve our efforts.A culture inspired by our values: put patients first, think independently, be radically transparent, every minute counts, and let the science speak.An unyielding commitment to always putting patients first.A de-centralized model that enables our program teams to focus on advancing science and helping patients.A place where you own the vision – both for your program and your own career path.A collaborative, fast-paced, data-driven environment where we inspire ourselves and each other to always perform at the top of our game.Access to learning and development resources to help you get in the best professional shape of your life.Robust and market-competitive compensation & benefits package.Flexible PTO.Rapid career advancement for strong performers.Potential ability to work on multiple GondolaBio Pharma programs across multiple therapeutic areas over time.Partnerships with leading institutions.Commitment to Diversity, Equity & Inclusion.The base pay range for this position is $150,000 to $200,000 per year. The actual compensation offered will be determined based on a number of job-related factors, including experience, skills, qualifications, and location. A bonus plan and equity will also be offered. #J-18808-Ljbffr