MSAT Scientist III

5 days ago


houston, United States Ehub Global Inc Full time

Title: MSAT Scientist III - 3 openings

Location: Houston, TX

Duration: 6m+

As a member of the MSAT Team, responsible for the successful transfer of viral vector bioprocesses into GMP production. Scientist III will ensure successful process scalability and manufacturability. Scientists in this role are responsible for all the process integration-related aspects of work during campaign preparation, process supervision, reporting during and after production campaigns, leading relevant major deviations and continuing manufacturing process improvement under the supervision of a Sr. Scientist and/or Manager.

  • This individual will utilize the process flow diagrams, learned expertise, and transferred data to transfer detailed, step-by-step manufacturing processes under the supervision of a senior MSAT scientist and/ or manager of MSAT.
  • This position has responsibilities that can be exemplified by the technology transfer of all aspects of buffer and media production, cell thaw and culturing, harvesting, purification, and/or bulk filling of drug substance.
  • This person will perform portions of process transfer from either PD or from customers. This individual will do this commensurate with their experience and under GMP conditions.
  • The position will support new product introductions (NPI/ technology transfers) with minimized assistance from the senior engineer associated with a project.
  • This position is likely to participate in more complex tasks such as the technology transfer and oversight, as well as process improvements, for all process steps.


Requirements:

  • MS or Ph.D. is preferred plus 5-10 years of experience
  • GMP manufacturing support (Viral Vector or Cell and Gene Therapy preferred; microbial or mammalian processing support required if VV/ CGT background is limited or non-existent), and basic understanding of current Good Manufacturing Practices, US / EU regulations.
  • Advanced knowledge of cellular biology, cell culture, scale up, mass transfer, bioreactor operation, and / or depth filtration, tangential flow filtration (TFF), chromatography, viral filtration; buffer and media production; aseptic processing


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