Pharmacology & Efficacy Scientist (In Vivo)

Get AI-powered advice on this job and more exclusive features. Direct message the job poster from ChemPartner About Us This is an exciting opportunity to join a dynamic team and contribute to the continued growth and success of ChemPartner, a leading China–based CRO and CDMO. ChemPartner is uniquely positioned be a true pharmaceutical alliance partner. With a team of over 1600 experienced scientists, western-trained pharmaceutical industry leaders, and experienced Pharmaceutical Executive Leadership at the helm, ChemPartner is dedicated to technically and strategically accomplish the research initiatives of pharma and biotech companies from around the world. Position Summary This position is responsible for designing and executing preclinical in vivo pharmacology studies to evaluate the efficacy, mechanism of action (MOA), and biomarkers of drug candidates. The successful candidate will be a key member of project teams, providing critical in vivo data to support target validation and candidate selection, and driving the progression of our R&D pipeline. Key Responsibilities Independently design and implement in vivo efficacy studies, including establishing and validating relevant disease animal models (e.g., subcutaneous/orthotopic xenograft models, transgenic models, disease induction models). Perform animal dosing via various routes of administration (e.g., IV, IP, SC, PO), collect and process various biological samples (blood, tissues), and monitor animal physiological and pathological parameters. Analyze samples using a variety of techniques (e.g., ELISA, Flow Cytometry, IHC, PCR), integrate data, interpret results, and evaluate the efficacy and MOA of drug candidates. Prepare detailed study protocols, experimental records, and final study reports. Clearly and effectively present scientific data and findings in team meetings and to multidisciplinary projects. Work closely with in vitro pharmacology, medicinal chemistry, biomarker, and toxicology teams to provide integrated scientific insights for project decision-making. Ensure all experimental activities strictly adhere to animal welfare and use protocols, biosafety guidelines, and company SOPs. Qualifications Education: Master’s or Ph.D. in Pharmacology, Immunology, Biochemistry, Life Sciences, or a related field. Work Experience: Master’s with 3+ years, or Ph.D. with 0-3 years of relevant in vivo pharmacology experience in industry or academia. Extensive hands‑on experience with rodent (mice/rats) in vivo techniques, including various routes of administration (e.g., IV, IP, SC, PO) and sample collection. Technical Knowledge and Skills: In-depth understanding of pharmacological principles and disease biology. Practical experience in establishing and running disease animal models, particularly in the field of [e.g., Oncology], is highly preferred. Proficient in in vivo data analysis and statistics. Experience with common in vitro and cell based assay techniques such as cell culture, Flow Cytometry, ELISA, IHC/IF is a plus. Strong problem‑solving skills and ability to work independently. Excellent teamwork and communication skills. Detail‑oriented with a high sense of responsibility and rigorous scientific attitude. Ability to work effectively in a fast‑paced, dynamic R&D environment. We Offer A competitive compensation and benefits package with performance-based bonuses. The opportunity to conduct cutting‑edge research in a dynamic scientific environment. Clear career progression paths and professional training opportunities. A collaborative, innovative, and supportive team culture. Seniority level Mid‑Senior level Employment type Full‑time Job function Research Referrals increase your chances of interviewing at ChemPartner by 2x Get notified about new Manager jobs in Boston, MA. #J-18808-Ljbffr