Consultant Scientist, CMC Pharmaceutics
3 weeks ago
The Loxo@Lilly CMC Pharmaceutics team has an exciting opportunity for an innovative individual to join our organization and develop the growing oncology portfolio of therapeutic small molecules. The individual will be responsible for aspects of API physicochemical characterization, preclinical and clinical drug product formulation development and stability testing.
"Work collaboratively with pharmaceutics, process chemistry and analytical chemistry teams to deliver data that supports oncology program development.
"Plan and conduct experiments on pre-formulation, characterization of API and the design of formulations such as suspensions, solutions, tablets, capsules, and spray dried dispersions.
"Assist in development of appropriate analytical test methods and stability studies for drug product formulations.
"Maintain laboratory notebook, laboratory equipment and chemical inventory.
"Provide written and verbal updates on assigned projects and activities as required.
"Author and review technical documents and formulation development reports.
Quals--
"Ph.D. in pharmaceutics, chemistry, material science, chemical engineering, or related discipline with 0-2 years experience, or Master s degree with 1-3 years of experience, or a Bachelor s degree with 1-5 years pharmaceutical industry experience.
"Excellent scientific knowledge in pre-formulation, material science, and formulation.
"Experience with chemistry techniques, solubility determination, compatibility studies, formulation screening, dissolution, polymorph screening and physicochemical characterization of API as well as formulations.
"Demonstrated ability to work well with other accomplished professionals within and across functions/teams.
"Strong written and oral communication skills.
"Experience with pharmaceutical data interpretation
"Demonstrable ability to work proactively, independently, and tenaciously.
"Experience in instrumental techniques such as XRPD, DSC, TGA, DVS, HPLC, SEM and Dissolution is highly desired.
"Experience in the formulation, process development and manufacturing of drug products.
"Ability to multi-task and shift priorities rapidly to meet tight deadlines.
"Detail oriented and well organized, good and thoughtful listener.
"Enthusiastic, self-motivated, and keen to improve processes, overcome inefficiencies and able to adapt to changing environment with ease.
"Proficient in Microsoft Office suite and applications.
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