Research Associate

3 weeks ago

Cambridge, United States The Fountain Group LLC Full time

The Fountain Group.  We are a national staffing firm and are currently seeking a ­­­­­­­­Research Assocaite for a prominent client of ours. This position is located in ­­Cambridge, MA. Details for the position are as follows:

Job Description:

  • This position offers the opportunity to impact a growing portfolio of targeted therapies in a fast-paced and innovative research environment.
  • We are searching for a dynamic Associate Biology Scientist with experience interrogating cellular and molecular mechanisms as they relate to kinase target pathway modulation, off-target liabilities, and resistance.
  • Independently, develop, optimize, and proactively troubleshoot cellular screening assays.
  • Responsible for generating, processing, interpreting, and presenting data in cross functional team meetings.
  • Proactively employ cell and molecular biology techniques, including gene targeting approaches and small molecule inhibition, to dissect mechanism of action.
  • Independently design, execute and document experiments to evaluate target dependency, off target liabilities, phenotypic responses and identifying resistance mechanisms.
  • Regularly share and present data with team members.

Qualifications:

  • What minimum qualifications do we require?
    • MS/BS in oncology, cellular biology, molecular biology, or related discipline with 3+ years of industry or relevant research experience.
    • Experience with cellular and molecular mechanisms as they relate to kinase target pathway modulation, off-target liabilities, and resistance.
    • Experience developing, optimizing, and troubleshooting cellular screening assays.
  • What additional qualifications will make you a stronger candidate?
    • Experience in developing and optimizing cell-based assays in multiple platforms (for example CTG, HTRF, AlphaLISA , FC, Jess-WB, NanoBret, Nanostring).
    • Experience with different molecular and cellular biology techniques (such as Western Blot).
    • Experience with genome editing (CRISPR or si/shRNA) for engineering cell line models is a plus.
    • Familiar with tumor models and establishing PK/PD/efficacy relationships and delivering PD readouts by western blots for in vivo tumor models.
    • Experience with standard software analytical tools, xlsx, Prism, or other synergy software.
    • Strong oral and written communication skills, as well as excellent documentation and organizational skills.
    • A team player, who listens effectively, invites response and discussion.
    • Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Compensation: $35-60 (rate should be commensurate with experience – must have decent amount of experience to come in closer to the top rate)

 

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