Senior Director Pharmacometrics, Clinical Pharmacology

4 weeks ago

Waltham, United States AstraZeneca PLC Full time

Senior Director Pharmacometrics, Clinical Pharmacology & Quantitative Pharmacology (CPQP)

Introduction to role:

Are you ready to embrace new and varied opportunities to develop and learn? We are seeking a strategic and scientific leader to join our Biopharmaceuticals R&D team. This role is accountable for the scientific strategy and quality of modelling & simulation (M&S) and other pharmacometrics (PMx) activities within the oncology TA. You will apply state-of-the-art M&S approaches to influence clinical study designs and internal/external decision making across the portfolio.

Accountabilities:

As a Senior Director, you will be responsible for developing a culture supportive of MIDD approaches within the TA, planning and executing state-of-the-art modeling and simulation (M&S) techniques, providing scientific and strategic input into pre-clinical, clinical, and post-approval development plans, and much more. You will also act as a delegate for the TA Head at functional and cross-function M&S and quantitative science meetings and initiatives as required.

Essential Skills/Experience:

* Significant demonstrated expertise within the field of modelling and simulation including PK, PKPD and statistics
* PhD degree or equivalent (M.Sc./Pharm.D.) required with relevant experience required
* Demonstrated broad translational and clinical development expertise and experience exemplified by at least 10 years international drug development experience (early and late), with emphasis on Pharmacometrics
* International scientific reputation gained from scientific publishing in the field on pharmacometrics
* Demonstrated ability to identify, develop and execute strategic M&S activities at level of portfolio
* Significant disease domain knowledge
* Relevant regulatory experience (written/oral)
* A demonstrated knowledge of regulatory, compliance, processes, standards and issues specific to pharmacometrics
* Strong leadership capabilities, including influencing skills
* Experience in mentoring and developing others
* Expert knowledge about relevant software and tools within the field of M&S

Desirable Skills/Experience:

* Experience in several organisations

At AstraZeneca, we follow the science to explore and innovate. We are working towards treating, preventing, modifying and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference. We have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs.

Are you ready to push the boundaries of science to deliver life-changing medicines? If your passion is science and you want to be part of a team that makes a bigger impact on patients' lives, then there's no better place to be.

Apply today

Date Posted

02-May-2024

Closing Date

02-Jun-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

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