Researcher

2 weeks ago

Bethesda, United States Veear Projects Inc Full time
Deliverables:
  • Clean Equipment - Ad-Hoc
  • Run Validation - Ad-Hoc
  • Inspect Equipment - Ad-Hoc
  • Meet with lab members to present updates - Ad-Hoc
Work Details:
  • 4. Examine the inositol polyphosphate levels of cells overexpressing the Pho86 protein which we have found bypasses a need for specific inositol polyphosphate kinases. Other mutants affecting prion propagation that show interactions with the inositol polyphosphate related genes will also be examined for their levels of these compounds. 1
  • 7. Seminar Attendance Attend LBG seminars and Wickner/Masison Joint Group seminars. 2
  • Keep various laboratory items in stock, and perform other tasks as directed. 3
  • Performs laboratory experiments in support of research programs and projects.
    • 1. Scientific Experiments Independently carry out experiments concerning prion proteins and anti-prion systems.
    • 2. Purify the various known prion proteins using affinity columns and examine whether they are capable of making amyloid in vitro, and, if so, whether this amyloid is infectious for yeast by using a yeast infectivity assay.
    • 3. Do transmission EM of the amyloid filaments if above infectious amyloid is made successfully to study the structure of this amyloid using solid-state NMR and cryoEM.
    • 4. Examine the inositol polyphosphate levels of cells overexpressing the Pho86 protein which we have found bypasses a need for specific inositol polyphosphate kinases. Other mutants affecting prion propagation that show interactions with the inositol polyphosphate related genes will also be examined for their levels of these compounds. 1
    • 5. Using the yeast knockout library, isolate mutants that increase the frequency of prions of Tup1 or Cyc8 and examine their mechanism of action.
    • 6. Laboratory Management Keep various laboratory items in stock and perform other tasks as directed.
    • 7. Seminar Attendance Attend LBG seminars and Wickner/Masison Joint Group seminars. 2
  • Contractor will attend LBG seminars and Wickner/Masison Joint Group seminars.
  • Maintains clear and accurate records of laboratory work in defined notebooks and converts those records to electronic records as appropriate.
  • Conduct data storage, and record keeping.
  • Perform data retrieval and entry using multiple IT systems.
  • Record and interpret experimental data.
  • Collect and analyze data; organize spreadsheets; prepare graphs, reports, summaries and illustrations for use and tracking of protocol activity.
  • Maintain and update laboratory notebook and database that includes a daily record of experiments; description of the overall analysis plan for each experiment, experimental methods/analysis plans, and results of experiments.
  • Provide preliminary descriptive analysis of study materials and methods.
  • Coordinate the collection and analysis of research data and analysis systems; ensure that all records are complete.
  • Review all records and make necessary notations before submitting them for interpretation.
  • Operates a variety of laboratory equipment.
  • Calibrate and operate a variety of laboratory instruments under GLP guidelines and follow SOPs to perform test, analysis, and other procedures.
  • Prepare, maintain, document and operate research tools and technologies.
  • Performs quality control of the laboratory including upkeep and routine maintenance of equipment.
  • Conduct and coordinate operations in research laboratory, including space, equipment use and scheduling.
  • Perform trouble shooting of equipment; document actions required to resolve problem and initiate corrective action as needed.
  • Perform required quality control steps as needed.
  • Calibrate and operate a variety of laboratory instruments used to perform tests, analyses, and other laboratory procedures.
  • Perform quality control of laboratory equipment.
  • Perform daily calibration, operation, and maintenance of laboratory equipment.
  • Monitor equipment performance and maintenance schedules; perform regularly scheduled maintenance on equipment and generate maintenance reports for equipment.
  • Orders and maintains laboratory supplies, including chemicals, biological materials, liquid nitrogen, etc.
  • Develop protocols into SOPs for use in training material.
  • Coordinate the day to day procurement functions within a research setting (i.e., laboratory).
  • Procure various types and categories of supplies, equipment, and services required by a research laboratory.
  • Initiate requests for new or renewal of standing orders for widely used supplies and services.
  • Interact with administrative staff on management and procurement issues.
  • Gather information and prepare procurement documents, including Statements of Work and justifications for a variety of supplies and services.
  • Research and prepare documents for the procurement supplies and research equipment/tools.
  • Prepare purchase requests for execution through procurement systems.
  • Order and maintain laboratory supplies, reagents and equipment.
  • Inventory laboratory supplies and equipment, make recommendations and prepare purchase requests.
  • Attends and presents data at laboratory meetings and one national scientific meeting.
  • Attend laboratory meetings; present findings to staff.
  • Prepare charts and figures for presentations and reports.
  • Attend facility staff meetings/reviews lab practices or review minutes of the meeting.
  • Prepare and present posters at scientific meetings.
  • Draft and produce reports, briefings and other materials for discussion with staff.
  • Prepare abstracts and manuscripts based on study data and experimental findings to be presented at scientific meetings and/or publication in scientific journals.
  • Attend conferences and seminars; read literature to remain current in related information.
  • Present findings describing outcomes of successful projects at meetings and conferences.
  • Develops laboratory experiments in support of research programs and projects.
  • Interpret experimental techniques and procedures; prepare reports on data results.
  • Conduct research including planning, and conducting experiments and data analysis in the Laboratory
  • Collaborate with investigators to carry out research testing in the clinical research laboratory according to written standard operating procedures (SOPs).
  • Perform experiments as listed in analysis plan.
  • Prepare a draft written description of the analysis procedures, the findings, the limitations and the proposal for followup experiments.
  • Perform both routine and specialized laboratory procedures of moderate to high complexity.
  • Design and perform experiments to advance laboratory goals
  • Perform experiments with all necessary controls; perform repeat experiments to determine reproducibility; design new experiments as necessary for progress.
  • Perform fundamental procedures required for research projects.
  • Perform routine experiments and tests; follow established procedures and protocols.
  • Coordinates quality control of the laboratory including upkeep and routine maintenance of equipment.
  • Conduct and coordinate operations in research laboratory, including space, equipment use and scheduling.
  • Perform trouble shooting of equipment; document actions required to resolve problem and initiate corrective action as needed.
  • Perform required quality control steps as needed.
  • Calibrate and operate a variety of laboratory instruments used to perform tests, analyses, and other laboratory procedures.
  • Perform quality control of laboratory equipment.
  • Perform daily calibration, operation, and maintenance of laboratory equipment.
  • Monitor equipment performance and maintenance schedules; perform regularly scheduled maintenance on
  • equipment and generate maintenance reports for equipment.
  • Reviews orders and maintains laboratory supplies, including chemicals, biological materials, liquid nitrogen, etc.
  • Develop protocols into SOPs for use in training material.
  • Coordinate the day to day procurement functions within a research setting (i.e., laboratory).
  • Procure various types and categories of supplies, equipment, and services required by a research laboratory.
  • Initiate requests for new or renewal of standing orders for widely used supplies and services.
  • Interact with administrative staff on management and procurement issues.
  • Gather information and prepare procurement documents, including Statements of Work and justifications for a variety of supplies and services.
  • Research and prepare documents for the procurement supplies and research equipment/tools.
  • Prepare purchase requests for execution through NIH procurement systems.
  • Order and maintain laboratory supplies, reagents and equipment.
  • Inventory laboratory supplies and equipment, make recommendations and prepare purchase requests.
  • Attends and / or presents data at laboratory meetings and one national scientific meeting.
  • Attend laboratory meetings; present findings to staff.
  • Prepare charts and figures for presentations and reports.
  • Attend facility staff meetings/reviews lab practices or review minutes of the meeting.
  • Prepare and present posters at scientific meetings.
  • Draft and produce reports, briefings and other materials for discussion with staff.
  • Prepare abstracts and manuscripts based on study data and experimental findings to be presented at scientific meetings and/or publication in scientific journals.
  • Attend conferences and seminars; read literature to remain current in related information.
  • Present findings describing outcomes of successful projects at meetings and conferences.
  • Develops strategies with supervisor and other laboratory personnel to plan subsequent experiments.
  • Conduct computerized searches of library references, scientific publications and other databases; extract, consolidate and organize pertinent materials.
  • Prepare written evaluation of results including detected deficiencies/defects, and reports on research protocols, processing, analysis, and storage.
  • Provide reference and research service in response to requests for information on biomedical subjects.
  • Review and discuss the results of experiments; propose and discuss possible new experiments.
  • Interact with scientists from other organizations or institutions involved in similar or related research projects.
  • Revise the analysis plan and experiments based on the findings of earlier experiments.
  • Collaborate with staff on planning and executing plans for the development of new research protocols and tools.
  • Evaluates and interprets computer analysis of research data and prepares data for publication.
  • Use the computer to cross reference design and repeat experiments and research before preparing findings for publication.
  • Cross reference research data; conduct comparative analysis.
  • Trains staff in specialized laboratory techniques, procedures and laboratory safety.
  • Train and mentor fellows and other scientists who work on project and use equipment; provide quality control measures; develop training plans; oversee training in laboratory techniques.
  • Provide training to students and other personnel in the use of laboratory equipment and in the performance of specialized procedures, techniques, etc.
  • Mentor graduate students or other junior staff to help them learn about assay development, lab equipment and guide their project structure.
  • Provide training to other personnel on specialized procedures, methodologies, etc.
  • Keep abreast of current research projects and to determine research assistance and information support.
  • Provide training in laboratory experiments to post-doctoral fellows and technicians.
  • Interact with students, post-doctoral fellows and non-doctoral research technicians on experimental design and laboratory-based methodologies.
  • Provide mentoring to post-baccalaureate students in the research group.
  • Create and educate lab members and colleagues in protocols for using new research technologies and tools.
1, 2, 3, 4, 5 represents priority rankings, where 1 is highest priority and 5 is lowest priority of those ranked

Minimum Education
  • Bachelor
Field of Study
Miscellaneous Health Medical Professions

  • Researcher

    2 weeks ago

    Bethesda, United States Veear Projects Inc Full time

    Deliverables: * Clean Equipment - Ad-Hoc * Run Validation - Ad-Hoc * Inspect Equipment - Ad-Hoc * Meet with lab members to present updates - Ad-Hoc Work Details: * 4. Examine the inositol polyphosphate levels of cells overexpressing the Pho86 protein which we have found bypasses a need for specific inositol polyphosphate kinases. Other mutants affecting...

  • Research Nurse

    2 weeks ago

    Bethesda, United States Akahi Associates, LLC Full time

    OverviewOverall Position Summary and Objectives: To provide services and deliverables through performance of support services. Minimum Qualifications: Bachelor's degree in nursing 4 years nursing experience Compensation/Benfits: Salary starting at $95,000.00 Healthcare Dental Vision 401(k) PTO Weekly Hours/Schedule: 30-40 hours per week ...

  • Research and Evaluation Specialist

    2 weeks ago

    Bethesda, United States Links Global Full time

    Links Global seeks a highly motivated and detail-oriented Research and Evaluation Specialist to join our team. The successful candidate will be crucial in designing, implementing, and overseeing research projects and evaluation initiatives. The position requires strong analytical skills, the ability to synthesize complex data, and a commitment to producing...

  • Research and Evaluation Specialist

    1 month ago

    Bethesda, United States Links Global Full time

    Job DescriptionJob DescriptionLinks Global seeks a highly motivated and detail-oriented Research and Evaluation Specialist to join our team. The successful candidate will be crucial in designing, implementing, and overseeing research projects and evaluation initiatives. The position requires strong analytical skills, the ability to synthesize complex data,...

  • Clinical Research Coordinator

    2 weeks ago

    Bethesda, United States Veear Projects Inc Full time

    Deliverables: Collect participant data; obtain informed consent/assent; respond to and report variances in protocol implement; collect and record research information, perform research procedures as qualified and assigned. - Ad-Hoc Manage conflicts/issues in clinical research setting; assess participants and families; provide verbal responses to...

  • Registered Nurse

    4 weeks ago

    Bethesda, United States Akahi Associates, LLC Full time

    Overview: **Job title**:Research Nurse **Overall Position Summary and Objectives**: To provide services and deliverables through performance of support services. **Min Education**: Associate's **Schedule**: Monday - Friday, regular office hours. No nights. **Benefits**: PTO, 11 paid Government Holidays, sick leave, health insurance, vision insurance,...

  • Clinical Research Coordinator

    1 week ago

    Bethesda, United States Veear Projects Inc Full time

    Deliverables: Collect participant data; obtain informed consent/assent; respond to and report variances in protocol implement; collect and record research information, perform research procedures as qualified and assigned. - Ad-Hoc Manage conflicts/issues in clinical research setting; assess participants and families; provide verbal responses to...

  • Research Associate II

    2 weeks ago

    Bethesda, United States Henry M. Jackson Foundation Full time

    Overview Join the HJF Team! HJF is seeking a Research Associate II to conduct qualitative and quantitative research in collaboration with other scientific and technical staff. The individual may lend expertise in the design, execution, and interpretation of military research studies. Research will align with the mission of CHAMP, as described below. This...

  • Registered Nurse

    2 weeks ago

    Bethesda, United States Akahi Associates, LLC Full time

    OverviewJob title: Research Nurse Overall Position Summary and Objectives: To provide services and deliverables through performance of support services. Min Education: Associate's Schedule: Monday - Friday, regular office hours. No nights. Benefits: PTO, 11 paid Government Holidays, sick leave, health insurance, vision insurance, dental insurance ...

  • Research Center Internship

    3 days ago

    Bethesda, United States Education Week Full time

    Job DescriptionJob DescriptionEducation Week, a nonprofit media organization that focuses on and is committed to K-12 education news, is seeking an intern to join our EdWeek Research Center team.  Job Summary The EdWeek Research Center Intern will work closely with a lively research staff to produce influential publications and web-based content that...

  • Researcher

    3 weeks ago

    Bethesda, United States VeeAR Projects Inc. Full time

    Title: : ResearcherDuration: 12 months contract with possible extensionLocation: Bethesda, MDWork Details:Examine the inositol polyphosphate levels of cells overexpressing the Pho86 protein which we have found bypasses a need for specific inositol polyphosphate kinases. Other mutants affecting prion propagation that show interactions with the inositol...

  • Researcher

    3 weeks ago

    Bethesda, United States VeeAR Projects Inc. Full time

    Title: : ResearcherDuration: 12 months contract with possible extensionLocation: Bethesda, MDWork Details:Examine the inositol polyphosphate levels of cells overexpressing the Pho86 protein which we have found bypasses a need for specific inositol polyphosphate kinases. Other mutants affecting prion propagation that show interactions with the inositol...

  • Researcher

    2 weeks ago

    Bethesda, United States VeeAR Projects Inc. Full time

    Title: : ResearcherDuration: 12 months contract with possible extensionLocation: Bethesda, MDWork Details:Examine the inositol polyphosphate levels of cells overexpressing the Pho86 protein which we have found bypasses a need for specific inositol polyphosphate kinases. Other mutants affecting prion propagation that show interactions with the inositol...

  • Research Coordinator II

    2 weeks ago

    Bethesda, United States Henry M. Jackson Foundation Full time

    Overview Join the HJF Team! HJF is seeking a Research Coordinator II to support research studies focused on pain at the Uniformed Services University (USU) and Walter Reed National Military Center (WRNMMC). This position will be in support of the Defense & Veterans Center for Integrative Pain Management (DVCIPM). The Henry M. Jackson Foundation for the...

  • Research Assistant I

    2 weeks ago

    Bethesda, United States Henry M. Jackson Foundation Full time

    Overview Join the HJF Team! HJF is seeking a Research Assistant I to perform research and/or development in collaboration with others for projects. The Research Assistant provides laboratory and technical support to senior technical and professional staff and solves less complex problems in carrying out research projects in a laboratory environment. This...

  • Research Associate I

    3 weeks ago

    Bethesda, United States Henry M. Jackson Foundation Full time

    Overview Join the HJF Team! HJF is seeking a Research Associate I to perform research and/or development in collaboration with other scientific and technical staff. Exercises technical discretion in the design, execution, and interpretation of experiments that contribute to project strategies. Performs limited analysis and interpretation of results. This...

  • Research Associate I

    3 weeks ago

    Bethesda, United States Henry M. Jackson Foundation for the Advancement of Military Medicine Full time

    Join the HJF Team! The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF) is a nonprofit organization dedicated to advancing military medicine. We serve military, medical, academic and government clients by administering, managing and supporting preeminent scientific programs that benefit members of the armed forces and civilians...

  • Research Associate I

    3 weeks ago

    Bethesda, United States Henry M. Jackson Foundation for the Advancement of Military Medicine Full time

    Join the HJF Team! The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF) is a nonprofit organization dedicated to advancing military medicine. We serve military, medical, academic and government clients by administering, managing and supporting preeminent scientific programs that benefit members of the armed forces and civilians...

  • Clinical Research Protocol Navigator

    1 week ago

    Bethesda, United States Veear Projects Inc Full time

    Work Details: Develop and review completed new and amended clinical research protocols and related documentation throughout the lifecycle of the study, with special attention to the accuracy, consistency, and completeness of documents. Develop new and review completed clinical research informed consent and other ethics and regulatory related...

  • Research Assistant II

    2 weeks ago

    Bethesda, United States Henry M. Jackson Foundation Full time

    Overview Join the HJF Team! The Research Assistant II is to perform research in collaboration with others for projects. The Research Assistant provides laboratory and technical support to senior technical and professional staff, and helps to carry out research projects in a laboratory enviroment. This position will be in support of the Department of...