Metabolomics Research Scientist

1 month ago

Lawrence, United States University of Kansas Full time

Job Description

80% - Metabolomics Research Projects & other small molecule analysis, including method development, sample preparation, analysis, data generation, utilization of software for analyzing data, report writing, manuscript writing support, attend research meetings.

* Design and execute metabolomics experiments to support metabolomic research projects.
* Perform LC-MS workflow for metabolomics including sample preparation, method development and execution, method validation, data acquisition and analysis, and final report writing.
* Demonstrate competency in troubleshooting, optimization, and implementation of challenging and innovative LC-MS/MS assays.

15% - Instrument maintenance and troubleshooting, general laboratory maintenance, writing and updating standard operating procedures, billing, supply ordering, receiving, and stocking.

* Operate and maintain mass spectrum system including but not limited to Thermo Q Exactive-HF, TSQ Altis plus triple quadrupole.
* Stay current with emerging metabolomics literature and technologies to ensure the MSAPL core remains at the forefront of the field.
* Setup targeted methods for environmentally relevant compounds.
* Maintain and document standard operating procedures; revise as needed.
* Track and maintain relevant Core documentation, including metabolomics service billing and requisitioning information.
* Monitor and maintain laboratory appearance.

5% - Mentor and train junior staff members in metabolomics and other relevant techniques and analysis

* Mentor and train junior staff members in metabolomics and other relevant techniques and analysis.
* Day to day supervision of junior MSAPL staff members' performance of metabolomics related activities.
* Provide advice on technical questions related to metabolomics and small molecules.
* Participate in relevant meetings/conferences.

Required Qualifications

* A doctorate or highest professional degree (including JD, MD, or international equivalents) in biochemistry, analytical chemistry or closely related field OR a Master's degree and three years of additional experience in biochemistry, analytical chemistry or closely related field.
* Coursework or work experience in untargeted and targeted metabolomics experiments, LC-MS method development, method validation and troubleshooting, as evidenced in application materials.
* Experience with metabolomics platforms including but not limited to Thermo Q Exactive-HF, TSQ Altis plus triple quadrupole, as evidenced in application materials.
* Graduate level coursework or previous work experience with data analysis and interpretation skills, including proficiency with statistical analysis software and metabolomics data analysis tools, as evidenced in application materials.
* Work experience that demonstrated the ability to stay current with relevant techniques and technologies as demonstrated in resume/work history.
* Graduate level coursework or work experience that demonstrated competency with liquid chromatography and mass spectrometry.
* Work experience that required excellent communication and collaboration skills with the ability to work effectively in a team-oriented environment, as demonstrated by work history.
* Work experience that required strong communication, organizational and interpersonal skills, as evidenced by application materials.

Preferred Qualifications

* PhD in biochemistry, analytical chemistry, or related field with a focus on metabolomics.
* Experience with Q-Exactive HF and TSQ Altis Plus Triple Quadrupole Mass Spectrometers.
* Experience with Vanquish LC system.
* Experience with Compound Discoverer, Skyline, LipidSearch analysis software and other Open-Source software.

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