Translational Engineering Principal Scientist

1 month ago


Providence, United States Allegis Global Solutions Full time
Translational Engineering Principal Scientist (Biomechanics)

General Summary: Engineering Sciences is seeking a Translational Engineering Senior Scientist to join the Biomechanics group within VCGT. The full-time role will support R&D initiatives with a focus on Device & Instrument Design. The successful candidate will have strong technical and product development skills and a demonstrable understanding of complex product innovation through FDA approval. Additionally, the candidate will have strong hands-on expertise in the mechanical assessment of devices, instruments, and drug-delivery platforms for clinical translation. This position is based in Providence, RI, and will report to the Associate Director, Translational Engineering.

Key Duties and Responsibilities:
  • Provide expertise on the mechanical aspects of device performance, including biomechanical assessment of a range of transplant sites with consideration of patient ambulation. 
  • Collaborate with the design and simulation team to identify critical structural and anatomical parameters for effective design. Evaluate the performance of device concepts and prototypes through hands-on evaluation and data interpretation to support design feedback.  
  • Work cross-functionally to assess surgical implications of device parameters in silico and small and large animals.  
  • Develop test methods for new and existing technology platforms and perform associated Technology Transfer activities. 
  • Design and implement standard and non-standard testing protocols to establish failure modes of device assemblies and components to provide possible solutions through design modifications.  
  • Identify, evaluate, and manage vendors to support early-mid phase device prototyping. 
  • Interface with the process and analytical development engineers to ensure design for manufacturing. 
 Knowledge and Skills: 
  • Strong knowledge and understanding of biomechanics, and structural mechanics (e.g., fatigue analysis, nonlinear materials). 
  • Proficient in designing detailed mechanical components using SolidWorks. 
  • Experience with FEA (e.g., ANSYS Mechanical), CFD (e.g., ANSYS Fluent, or Star-CCM+) 
  • Excellent knowledge of mechanical engineering design concepts, ASTM standards, design control, and tolerance analysis. 
  • Strong understanding of implantable materials and best practices to develop medical devices and support submissions to regulatory bodies and governmental agencies. 
  • Excellent verbal / written communication skills and ability to quantify experimental results and present to cross-functional groups effectively. 
  • Demonstrated excellence in planning, executing, and analyzing experiments. 
  • Project management skills with flexibility to multi-task and adapt to evolving priorities. 
 Education and Experience: 
  • Ph.D. in Mechanical Engineering, Biomedical Engineering, Materials Science, or related field. 
  • 4-7 years (Ph.D.) or 7+ years (MS) industry experience in medical device and combination product research and development, including mechanical components and fixture designs.  

Company Information:Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, by applicable law. Please note that Vertex requires COVID-19 vaccination for all employees working in the U.S. as a condition of employment at Vertex, subject to medical, religious, or other accommodations or exemptions required by law. We believe this requirement is vital to keeping everyone at Vertex and in our communities safe. This requirement applies to both existing and new employees who may at any time work on-site at a Vertex facility or visits another location on behalf of Vertex (e.g., conferences, customer visits, etc.), including all remote employees. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.

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