Senior Research Associate

4 weeks ago


seattle, United States SciPro Full time

SciPro is thrilled to be partnered with one of Seattle's best up-and-coming biotech organizations at the forefront of developing innovative therapies for incurable cancers.


My client is a an early-stage biotech company that looks to harness cutting-edge proteomics and AI to unlock previously inaccessible targets in cancer. Exciting opportunities await—you could be part of something transformative


Job Description:

The team are seeking a Senior Research Associate (Sr RA) to work directly with their platform and proteomics group. The ideal candidate is results-driven, and eager to contribute in a small preclinical biotech environment.


Key Responsibilities:

  • LC-MS Operation & Maintenance: Operate, maintain, and troubleshoot mass spectrometers (Orbitrap and Q-TOF) and liquid chromatography systems.
  • Sample Preparation: Execute protocols for protein extraction, digestion (e.g., trypsin), and clean-up for LC-MS/MS analysis.
  • Proteomics Analysis: Conduct complex proteomics experiments using DIA, DDA, and PRM approaches.
  • Method Development: Assist in developing and optimizing proteomics methods, including sample preparation and LC-MS methods.
  • Data Analysis & Interpretation: Analyze proteomics data using software (e.g., Skyline) and bioinformatics tools to identify changes in protein and peptide expression.
  • Collaborative Research: Work closely with cross-functional teams to design and execute experiments and interpret results.
  • Documentation & Reporting: Maintain detailed experimental records, analyze and interpret data, and present findings at internal meetings and external conferences.


Qualifications:

Required:

  • Education: BS degree in biology, chemistry, or a related field with 3 years of relevant experience; or an MS degree with 1 year of experience in proteomics and mass spectrometry.
  • Mass Spectrometry Experience: Significant hands-on experience with LC-MS/MS systems (e.g., Orbitrap, Q-TOF), including operation, maintenance, and troubleshooting.
  • Sample Preparation Skills: Expertise in cell culture, protein extraction, digestion, and peptide clean-up for MS analysis.
  • Data Analysis Tools: Proficiency with proteomics data analysis software (e.g., Skyline) and a solid understanding of proteomics data analysis.
  • Technical Problem-Solving: Demonstrated ability to troubleshoot instrumentation issues and optimize methods for challenging samples.
  • Communication Skills: Excellent verbal and written communication skills, with the ability to present complex data clearly to both technical and non-technical audiences.


If you are interested, please do not hesitate to reach out as my client is currently conducting interviews as we speak



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