Senior Research Associate
4 weeks ago
SciPro is thrilled to be partnered with one of Seattle's best up-and-coming biotech organizations at the forefront of developing innovative therapies for incurable cancers.
My client is a an early-stage biotech company that looks to harness cutting-edge proteomics and AI to unlock previously inaccessible targets in cancer. Exciting opportunities await—you could be part of something transformative
Job Description:
The team are seeking a Senior Research Associate (Sr RA) to work directly with their platform and proteomics group. The ideal candidate is results-driven, and eager to contribute in a small preclinical biotech environment.
Key Responsibilities:
- LC-MS Operation & Maintenance: Operate, maintain, and troubleshoot mass spectrometers (Orbitrap and Q-TOF) and liquid chromatography systems.
- Sample Preparation: Execute protocols for protein extraction, digestion (e.g., trypsin), and clean-up for LC-MS/MS analysis.
- Proteomics Analysis: Conduct complex proteomics experiments using DIA, DDA, and PRM approaches.
- Method Development: Assist in developing and optimizing proteomics methods, including sample preparation and LC-MS methods.
- Data Analysis & Interpretation: Analyze proteomics data using software (e.g., Skyline) and bioinformatics tools to identify changes in protein and peptide expression.
- Collaborative Research: Work closely with cross-functional teams to design and execute experiments and interpret results.
- Documentation & Reporting: Maintain detailed experimental records, analyze and interpret data, and present findings at internal meetings and external conferences.
Qualifications:
Required:
- Education: BS degree in biology, chemistry, or a related field with 3 years of relevant experience; or an MS degree with 1 year of experience in proteomics and mass spectrometry.
- Mass Spectrometry Experience: Significant hands-on experience with LC-MS/MS systems (e.g., Orbitrap, Q-TOF), including operation, maintenance, and troubleshooting.
- Sample Preparation Skills: Expertise in cell culture, protein extraction, digestion, and peptide clean-up for MS analysis.
- Data Analysis Tools: Proficiency with proteomics data analysis software (e.g., Skyline) and a solid understanding of proteomics data analysis.
- Technical Problem-Solving: Demonstrated ability to troubleshoot instrumentation issues and optimize methods for challenging samples.
- Communication Skills: Excellent verbal and written communication skills, with the ability to present complex data clearly to both technical and non-technical audiences.
If you are interested, please do not hesitate to reach out as my client is currently conducting interviews as we speak
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