Associate Director, Computational Genomics, Next Generation Cell Therapy

Associate Director, Computational Genomics, Next Generation Cell Therapy page is loaded Associate Director, Computational Genomics, Next Generation Cell Therapy Apply locations Boston, MA time type Full time posted on Posted 13 Days Ago job requisition id REQ-23607

Job Description

We are seeking a computational biologist with expertise in driving forward biological discoveries to join Vertex. This position is part of a global Data and Computational Sciences team focused on developing cell and genetic therapy treatments of serious human diseases. You will lead a group of computational biologists using genomic data dedicated to discovering and actualizing the next generation of cell therapies that will be transformative treatments for patients. By collaborating with project teams, you and your team will innovate to overcome challenges, and pioneer scientific breakthroughs and discoveries, using genetic and genomic data . Your leadership skills, critical and strategic thinking, proactive communication, and seamless cross-functional collaboration will be critical to your success in this role.

Key responsibilities:

• S ets strategy and oversees execution of genomic and transcriptomic analyses, to enable our next generation of cell therapies.
• Identifies strategic opportunities and proposes plans, tactics, and investments for maximum impact of the team for data-driven decision-making from genomic and genetic data, including cross-functional impact with Research, Preclinical and CMC teams.
• Leverages computational expertise across the breadth of Data and Computational Sciences team to identify opportunities for furthering cell therapy projects.
• Establishes and maintains productive relationships with key stakeholders across Vertex
• Assigns group members to serve on project teams and ensures continuous alignment between the team and broader site goals
• Provides strong leadership and a focus on continuous talent development to attract and retain top talent in a highly competitive environment
• Mentors the development of others, motivates personnel, and resolves conflicts
• Ensures goal setting of team members is effectively linked to corporate and department goals
• Constructs draft budgets and manages execution of approved budgets and hiring for the group(s)
• Oversees activities and resourcing of the team, adapting to changing priorities, to ensure key goals of critical projects are met on time
• Oversees effective management of group(s)’ CRO contracts and/or external scientific collaborations
• Ensures analyses from team meet stage-appropriate standards for data integrity and documentation
• Leads preparation of clear scientific reports with cross-functional collaborators, and clearly communicates key information to leadership and team members to enable decision-making

Minimum Qualifications:

• PhD degree (or Master’s degree) in computational biology, human genetics, genomics, systems biology or a related field with 5-8 years of work experience and 2 years of management experience, or the equivalent combination of education and experience 
• Experience in leading and developing high performance teams.
• Advanced understanding in the fields of genomics, statistics and computational biology, especially in areas key to advancing our cell therapy portfolio, such as bulk and single cell transcriptomic characterization of cells, as well as analysis of proteomic data.
• A proven track record in the analysis, visualization, and interpretation of large scale genomic data in a drug development context. 
• Demonstrated ability to work across cross-functional teams, ensuring timely progress
• Ability to identify gaps and propose solutions around current genomic analyses, including bringing in new technologies and capabilities when appropriate
• Superior communication skills, demonstrating confidence and versatility in presenting verbally to diverse audiences and writing technical documents
• A team-oriented growth mindset that welcomes feedback from others and supports other team members; a positive attitude that enthusiastically tackles and overcomes challenges
• Highly skilled in mentoring others, resolving technical problems, maintaining procedural and ethical standards, and cultivating healthy team morale

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as: 
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia — and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency .

Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com  or follow us on Facebook , Twitter/X ,  LinkedIn ,  YouTube  and  Instagram .

The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives. 

Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.

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