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2 weeks ago
Software Guidance & Assistance, Inc., (SGA), is searching for a Research Associate for a CONTRACT assignment with one of our premier Pharmaceutical Services clients in San Francisco, CA.
Responsibilities :
- Purify membrane proteins from E coli, Insect, or Mammalian cell expressions and characterize protein quality using various biophysical and biochemical methods.
- Expected to perform mammalian cell culture work and optimize protocols for protein expression as well as for automation of protein purification.
Required Skills:
- Must have either a BS/MS degree with 6-10 years of experience or a PhD with 4 years of experience in Biochemistry, Chemical Biology, Structural Biology or a related discipline.
- Working knowledge of protein expression systems such as mammalian, insect, E coli with a focus on membrane proteins.
- Hands-on experience in membrane protein purification
- Knowledgeable with diverse chromatography techniques and AKTA chromatography systems
- Basic mammalian cell culture (in particular suspension HEK293) experience.
- Proficiency with methods to characterize protein quality and purity, such as FSEC, DSF/thermal shift, DLS, etc.
- Expertise with biophysical and biochemical protein-protein interaction techniques and/or functional assays.
- Experience with basic lab automation.
- Passion for exploring and developing new technologies.
- Self-motivated, hard-working, dynamic and curious person with good communication and problem-solving skills
- Team-oriented and collaborative.
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