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Scientist/Senior Scientist
4 months ago
Scientist/Senior Scientist
Full-Time
Exton PA
Frontage Laboratories
Frontage Laboratories is a CRO / Clinical Research Organization providing integrated, science-driven, product development services throughout the drug discovery and development process to enable life science companies to achieve their drug development goals. We have enabled many innovator, generic and consumer health companies of all sizes to file IND, NDA, ANDA, BLA and 505(b)(2) submissions in global markets allowing for successful development of important therapies and products for patients. We are committed to providing rigorous scientific expertise to ensure the highest quality and compliance. We have successfully assisted clients to advance hundreds of molecules through development to commercial launch in global markets. Come and join us to make a world of difference.
Responsibilities:
1. Intact protein mass analysis using mass spectrometry (HPLC-Q-TOF MS)
- QC analysis and high throughput analysis for non-multispecific panels (mAbs, Fabs, scfv)
2. Data analysis, Documentation, and reporting – ELNs, etc.,
3. Lab instrument maintenance – General ESI source cleaning and routine calibration
4. Prepare HPLC solvents and replenish as needed
5. Prepare general buffers and reagents for enzymatic digestions and assays etc
6. MS Lab-specific supply maintenance – inventory and ordering
7. Chemical inventory for EHS
8. Perform peptide mapping, if applicable
Additional Duties:
1. Support assay development, validation, and bioanalysis efforts, as needed.
2. Assist in drafting and executing peer-reviewed posters, manuscripts, tech reports, and patent filings.
3. Attend in-house seminars to support team goals.
Work experience Requirements:
Experience with mass spectrometry is required. Previous experience handling and working with proteins using general protein biochemistry techniques including but not limited to aliquoting and pipetting is required. Pharmaceutical experience working with antibodies is preferred. Candidate must be highly organized, independent, and very detail oriented.
Education Requirements:
Ph.D. with 0-2 years experience, or MS with 3-5 years experience, or a B.S. with 10+ years in an analytical chemistry discipline.
Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
