Senior Scientist, Cellular Resilience

19 hours ago


Waltham MA United States AstraZeneca Full time

Senior Scientist, Cellular Resilience

Waltham, MA

Join AstraZeneca, a global leader in pharmaceutical innovation, where we are committed to making an impact and finding answers to challenges. We are seeking a highly motivated Senior Scientist with a broad background in implementing novel model systems in vitro and assessing in vivo studies. As a key member of our discovery team based in Waltham, MA, you will drive projects through the drug discovery process, delivering datasets that directly impact our efforts.

Accountabilities:

In this laboratory-based position, you will develop, conduct, and analyze in vitro experiments to assess the function of our candidate drugs. You will support cross-functional teams and collaborate with colleagues to ensure the timely generation and dissemination of critical program data. Your role will also involve reviewing emerging literature and internal data to help identify new potential targets and contribute to target validation activities.

Essential Skills/Experience:

  • PhD in a relevant field with 0-3 years' experience with in vitro model development or MS in a relevant field with 3-5 years' experience developing novel in vitro cellular and molecular models, or BS in a relevant field with 5-8 years’ experience developing novel in vitro cellular and molecular models
  • Demonstrated ability to model complex biological axes in vitro
  • Demonstrated experience with genome editing techniques and epigenetics
  • Strong background in cellular function assays, including cell viability analysis and flow cytometry
  • Preference for experience with techniques to assess senescence (immune-specific and/or cellular)
  • Ability to independently design and execute research plans for one or more programs, and to review, analyze, and interpret experimental results rapidly
  • Ability to draft, execute and record protocols and experiments in a timely manner and maintain an excellent laboratory notebook
  • Proven track record of success in your research and experience preparing written scientific reports and oral presentations

Desirable Skills/Experience:

  • Strong interpersonal, influencing, negotiating and collaboration skills together with evidence of having used these to support problem solving and delivery in a team-oriented, collaborative environment

At AstraZeneca's Oncology R&D department, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. We are united in our vision to eliminate cancer as a cause of death. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next.

Ready to join us on this mission? Apply now

If you’re curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.

Closing Date: December 6, 2024

Competitive remuneration and benefits apply

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.

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